Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Brookline | Anaheim Regional Transportation Intermodal Center | Cheapest | ||||
 | Bus | Boston (South Station) | Santa Ana Bus Station | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Boston (South Station) | Anaheim Regional Transportation Intermodal Center | No tags | ||||
| Bus | Boston (South Station) | Anaheim Regional Transportation Intermodal Center | No tags | ||||
| Bus | Boston (South Station) | Anaheim Regional Transportation Intermodal Center | No tags |
Last refresh of the prices: Last Tuesday at 02:06 EST.
Get from Boston to Santa Ana
The journey takes about 3 days, 9 hours 30 minutes, and with fares starting at just €196, it presents an excellent value for a comfortable ride.
Where are the popular stops in Boston and Santa Ana?
Stops in Boston
- A145 Dartmouth St, Boston, MA 02116, USA
- B100 Legends Way, Boston, MA 02114, USA
- C335 Grove St, Auburndale, MA 02466
- D
Prudential MBTA Station
220 Huntington Ave, Boston, MA 02115, USA - E
Copley MBTA Station
650 Boylston St, Boston, MA 02116, USA - F
Long Wharf
66 Long Wharf, Boston, MA 02110, USA
Stops in Santa Ana
- A
Santa Ana Greyhound Bus Station
1000 E Santa Ana Blvd, Santa Ana, CA 92701 - B
602 S Main St
602 S Main St, Santa Ana, CA 92701, USA
Compare bus companies
Based on 87519 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at €196
Frequently asked questions about travelling by bus from Boston, MA, US to Santa Ana, US
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Boston to Santa Ana?
The cheapest coach tickets from Boston to Santa Ana start from €196. The average price for this route is around €201. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Boston to Santa Ana?
The average bus journey time from Boston to Santa Ana is 3d 9h, covering a distance of 4158 km. The fastest bus can take you there in 3d 2h and is operated by Greyhound.
Which bus companies service the Boston to Santa Ana route?
Several major bus companies operate on this route with 13 buses available per day.
What is the earliest and latest departure time for the bus from Boston to Santa Ana?
The earliest bus departs from Boston to Santa Ana at 01:30. And the latest bus departs at 21:50.
What are the CO₂ emissions for the bus trip from Boston to Santa Ana?
A bus journey from Boston to Santa Ana produces an estimated 104 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Boston, MA, US to Santa Ana, US was searched and found on 1 Feb 2026 with a price of €194To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston, MA, US to Santa Ana, US as early as possible.
You can expect to pay from €194 to €262 for a bus ticket from Boston, MA, US to Santa Ana, US based on the last 2 days. You can expect to find the cheapest price for the trip at €195, which is on 2026-02-02.
