Train from Brussels to Prague: Tickets & Timetables

Next train departures

Next departures from Brussels to Prague on 28 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
European SleeperTrain
    Brussels South/Midi Train Station
    Hlavní nádražíCheapestFastest

    Last refresh of the prices: Today at 21:43 CET.

    Compare 2 ways to travel from Brussels to Prague

    We recommend taking the bus

    Among the sustainable travel choices, the bus stands out as a good way to reach Prague. The journey takes about 19 hours 15 minutes and with fares starting at just £35, it presents an excellent value for a comfortable ride.

    31bus per day
    19h 15mAverage duration
    445 milesDistance
    18kgCO₂ emissions
    Average price£35 - £157Average duration19h 15m
    18kg CO₂e
    Average price£50 - £231Average duration14h 36m
    17kg CO₂e

    Frequently asked questions about travelling from Brussels to Prague by train

    1. How much does a cheap train ticket from Brussels to Prague cost?

      The average train ticket price from Brussels to Prague is £110. The best way to find cheap train tickets from Brussels to Prague is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

    2. How long is the train trip from Brussels to Prague?

      A train trip between Brussels and Prague is around 14h 36m, although the fastest train will take about 11h 11m. This is the time it takes to travel the 446 miles that separates the two cities.

    3. How many daily train are there between Brussels and Prague?

      The number of trains from Brussels to Prague can differ depending on the day of the week. On average, there are 6. Some trains are direct while others include transferring trains. Simplify your train trip from Brussels to Prague by comparing and selecting the train that fits your travel style and budget on Busbud.

    4. Which train companies travel from Brussels to Prague?

      When taking the train from Brussels to Prague, you can travel comfortably and safely with Deutsche Bahn.

    5. What are the departure and arrival stations for a train from Brussels to Prague?

      Trains travelling between Brussels and Prague leave from Brux-Nord or Brussels South (Gare du Midi) and arrive at Hlavní nádraží, Florenc, PRG Airport.

    Find cheapest prices for trains

    Price is for a one-way ticket for one passenger and based on past searches.

    Best price found
    25/11
    No data
    26/11
    £184
    Today
    No data
    28/11
    £194
    29/11
    No data
    30/11
    No data
    01/12
    £194
    02/12
    No data
    busbud logoThe cheapest trip from Brussels to Prague was searched and found on 26 Nov 2025 with a price of £184

    To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Brussels to Prague as early as possible.

    You can expect to pay from £184 to £875 for a train ticket from Brussels to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at £194, which is on 2025-11-28.

    People from around the world trust Busbud