Train from Prague to Brussels: Tickets & Timetables

Next train departures

Next departures from Prague to Brussels on 20 December
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
EuroCity Train + Deutsche Bahn ICE + InterCity
Train
Hlavní nádraží
SchaarbeekCheapest
EuroCity Train + Deutsche Bahn ICE + InterCity
Train
Hlavní nádraží
Brussels Central Train StationFastest
EuroCity Train + Deutsche Bahn ICE + InterCity
Train
Hlavní nádraží
SchaarbeekNo tags
EuroCity Train + Deutsche Bahn ICE + InterCity
Train
Hlavní nádraží
SchaarbeekNo tags
EuroCity Train + Deutsche Bahn ICE + InterCity
Train
Hlavní nádraží
SchaarbeekNo tags

Last refresh of the prices: Last Tuesday at 16:03 CET.

Compare 2 ways to travel from Prague to Brussels

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Brussels. The journey takes about 18 hours 40 minutes and with fares starting at just £34, it presents an excellent value for a comfortable ride.

17bus per day
18h 40mAverage duration
440 milesDistance
18kgCO₂ emissions
Average price£34 - £190Average duration18h 40m
18kg CO₂e
Average price£47 - £232Average duration15h 18m
17kg CO₂e

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
17/12
No data
18/12
£120
Today
No data
20/12
No data
21/12
£194
22/12
No data
23/12
£83
24/12
No data
busbud logoThe cheapest trip from Prague to Brussels was searched and found on 23 Dec 2025 with a price of £83

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Prague to Brussels as early as possible.

You can expect to pay from £83 to £877 for a train ticket from Prague to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at £83, which is on 2025-12-23.

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