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Compare 2 ways to travel from Spartanburg to Indianapolis

Bus
Average priceUS$124 - US$159Average duration17h 5m
16kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average priceUS$159 - US$159Average duration1d 2h
59kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Spartanburg to Indianapolis

Among the sustainable travel choices, the bus stands out as a good way to reach Indianapolis. The journey takes about 17 hours 5 minutes and with fares starting at just US$124, it presents an excellent value for a comfortable ride.

7bus per day
17h 5mAverage duration
US$124Cheapest ticket
16kgCO₂ emissions

Bus Spartanburg to Indianapolis: Trip Overview

Average ticket priceUS$134
Average bus trip duration17h 5m
Number of daily buses7
Earliest bus departure06:05
Distance400 miles
Latest bus departure21:00

Spartanburg to Indianapolis Bus

Busbud helps you find a bus from Spartanburg to Indianapolis. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Spartanburg to Indianapolis from the most reliable bus companies operating this trip.

Discover how much the bus trip from Spartanburg to Indianapolis will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Spartanburg - Indianapolis

  1. How far is Indianapolis from Spartanburg by coach?

    The distance between Spartanburg and Indianapolis by coach is approximately 406 miles (654 km).

  2. Is there a way to reach Indianapolis from Spartanburg without flying?

    You have the option to select the coach for your journey on this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
23/06
US$126
24/06
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26/06
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busbud logoThe cheapest trip from Spartanburg to Indianapolis was searched and found on 23 Jun 2025 with a price of US$126

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Spartanburg to Indianapolis as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Spartanburg and Indianapolis!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Spartanburg to Indianapolis, get comfy and count the stars.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Spartanburg to Indianapolis will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Spartanburg to Indianapolis.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

What's the cheapest way to go from Spartanburg to Indianapolis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Spartanburg by bus?

Bus from Spartanburg to Indianapolis

You can also go to Indianapolis by train

Train from Spartanburg to Indianapolis

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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