Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | San Antonio Bus Station | Downtown Transit Center | Cheapest | ||||
Greyhound Lines Mexico + Greyhound Lines, Inc. | Bus | San Antonio Bus Station | Indianapolis Bus Station | Fastest | ||||
Greyhound Lines Mexico + Greyhound Lines, Inc. | Bus | San Antonio Bus Station | Indianapolis Bus Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | San Antonio Bus Station | Indianapolis Bus Station | No tags | ||||
Valley Transit + Greyhound Lines, Inc. | Bus | San Antonio Bus Station | Indianapolis Bus Station | No tags |
Last refresh of the prices: Today at 09:05 CST.
Compare 2 ways to travel from San Antonio to Indianapolis
Among the sustainable travel choices, the bus stands out as a good way to reach Indianapolis. The journey takes about 1 day, 6 hours 30 minutes and with fares starting at just £98, it presents an excellent value for a comfortable ride.
Where are the popular stops in San Antonio and Indianapolis?
Stops in San Antonio
- A500 N St Mary's St, San Antonio, TX 78205, USA
- B7914 Interstate 35 Access Rd, San Antonio, TX 78224, USA
- C165 Bowie St, San Antonio, 78205
- D4407 S PanAm Expy #101, San Antonio, TX 78225, USA
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Frequently asked questions about travelling by bus from San Antonio, US to Indianapolis
How far is Indianapolis from San Antonio by coach?
The distance between San Antonio and Indianapolis by coach is approximately 999 miles (1611 km).
Is there a way to reach Indianapolis from San Antonio without flying?
You have the option to select the coach for your journey on this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Antonio, US to Indianapolis was searched and found on 26 Nov 2025 with a price of £122To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Antonio, US to Indianapolis as early as possible.
You can expect to pay from £122 to £280 for a bus ticket from San Antonio, US to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at £122, which is on 2025-11-26.
What's the cheapest way to go from San Antonio, US to Indianapolis?
The bus is the cheapest travel choice for this destination
