Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Pittsburgh Intermodal Station | Gateway Station | CheapestFastest | ||||
| Bus | Pittsburgh Intermodal Station | Gateway Station | No tags | ||||
 | Bus | Pittsburgh Intermodal Station | Gateway Station | No tags | ||||
| Bus | Pittsburgh Intermodal Station | Gateway Station | No tags |
Last refresh of the prices: Yesterday at 18:58 EST.
Compare 2 ways to travel from Pittsburgh to St. Louis
Among the sustainable travel choices, the bus stands out as a good way to reach St. Louis. The journey takes about 13 hours 35 minutes and with fares starting at just £48, it presents an excellent value for a comfortable ride.
Where are the popular stops in Pittsburgh and St. Louis?
Stops in Pittsburgh
- A55 11th St, Pittsburgh, PA 15222, USA
- B
Sennott Square
201 S Bouquet St, Pittsburgh, PA 15213, USA
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Frequently asked questions about travelling by bus from Pittsburgh to St. Louis
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Pittsburgh to St. Louis?
The cheapest coach tickets from Pittsburgh to St. Louis start from £48. The average price for this route is around £73. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Pittsburgh to St. Louis?
The average bus journey time from Pittsburgh to St. Louis is 13h 35m, covering a distance of 557 miles. The fastest bus can take you there in 11h 55m and is operated by Greyhound.
Which bus companies service the Pittsburgh to St. Louis route?
What is the earliest and latest departure time for the bus from Pittsburgh to St. Louis?
The earliest bus departs from Pittsburgh to St. Louis at 01:35. And the latest bus departs at 20:00.
What are the CO₂ emissions for the bus trip from Pittsburgh to St. Louis?
A bus journey from Pittsburgh to St. Louis produces an estimated 22 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Pittsburgh to St. Louis?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.
Which company has the best Wi-Fi from Pittsburgh to St. Louis?
Based on Busbud reviews, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Pittsburgh to St. Louis?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Pittsburgh to St. Louis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Pittsburgh to St. Louis was searched and found on 1 Dec 2025 with a price of £48To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pittsburgh to St. Louis as early as possible.
You can expect to pay from £48 to £181 for a bus ticket from Pittsburgh to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at £48, which is on 2025-12-01.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Pittsburgh to St. Louis?
The bus is the cheapest travel choice for this destination
