What's the distance between Pittsburgh and Chicago by coach?

The journey from Pittsburgh to Chicago by coach covers an approximate distance of 410 miles (661 km).

What is the best way to go from Pittsburgh to Chicago without flying?

You can choose the coach to travel this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You also have the option of utilising carpooling services.

Bus Pittsburgh to Chicago from £44 | Refundable Tickets

Next bus departures

Next departures from Pittsburgh to Chicago on 20 November
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	19:45	Pittsburgh Intermodal Station	11h 25m	06:10	Downtown Greyhound Station	Cheapest
Bus	19:45	Pittsburgh Intermodal Station	10h 55m	05:40	Chicago 95Th & Dan Ryan	Fastest
Bus	18:30	Pittsburgh Intermodal Station	14h 20m	07:50	537-517 W. Jackson Blvd	No tags

Next departures from Pittsburgh to Chicago on 21 November
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	19:45	Pittsburgh Intermodal Station	11h 25m	06:10	Downtown Greyhound Station	Cheapest
	Bus	00:40	Pittsburgh Intermodal Station	10h 20m	10:00	Downtown Greyhound Station	Fastest
	Bus	01:35	Pittsburgh Intermodal Station	14h	14:35	Downtown Greyhound Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	00:40	Pittsburgh Intermodal Station	13h 45m	13:25	Chicago 95Th & Dan Ryan	No tags
	Bus	19:45	Pittsburgh Intermodal Station	10h 55m	05:40	Chicago 95Th & Dan Ryan	No tags

Next departures from Pittsburgh to Chicago on 22 November
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	19:45	Pittsburgh Intermodal Station	11h 25m	06:10	Downtown Greyhound Station	Cheapest
	Bus	00:40	Pittsburgh Intermodal Station	10h 20m	10:00	Downtown Greyhound Station	Fastest
	Bus	01:35	Pittsburgh Intermodal Station	14h	14:35	Downtown Greyhound Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	00:40	Pittsburgh Intermodal Station	13h 45m	13:25	Chicago 95Th & Dan Ryan	No tags
	Bus	19:45	Pittsburgh Intermodal Station	10h 55m	05:40	Chicago 95Th & Dan Ryan	No tags

Next departures from Pittsburgh to Chicago on 23 November
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	19:45	Pittsburgh Intermodal Station	11h 25m	06:10	Downtown Greyhound Station	Cheapest
	Bus	00:40	Pittsburgh Intermodal Station	10h 20m	10:00	Downtown Greyhound Station	Fastest
	Bus	01:35	Pittsburgh Intermodal Station	14h	14:35	Downtown Greyhound Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	00:40	Pittsburgh Intermodal Station	13h 45m	13:25	Chicago 95Th & Dan Ryan	No tags
	Bus	19:45	Pittsburgh Intermodal Station	10h 55m	05:40	Chicago 95Th & Dan Ryan	No tags

Next departures from Pittsburgh to Chicago on 24 November
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	07:40	Pittsburgh Intermodal Station	13h 25m	20:05	Downtown Greyhound Station	Cheapest
	Bus	00:40	Pittsburgh Intermodal Station	10h 20m	10:00	Downtown Greyhound Station	Fastest
	Bus	01:35	Pittsburgh Intermodal Station	14h	14:35	Downtown Greyhound Station	No tags
	Bus	19:45	Pittsburgh Intermodal Station	11h 25m	06:10	Downtown Greyhound Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	00:40	Pittsburgh Intermodal Station	13h 45m	13:25	Chicago 95Th & Dan Ryan	No tags

Next departures from Pittsburgh to Chicago on 25 November
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	00:40	Pittsburgh Intermodal Station	10h 20m	10:00	Downtown Greyhound Station	CheapestFastest
	Bus	01:35	Pittsburgh Intermodal Station	14h	14:35	Downtown Greyhound Station	No tags
	Bus	19:45	Pittsburgh Intermodal Station	11h 25m	06:10	Downtown Greyhound Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	00:40	Pittsburgh Intermodal Station	13h 45m	13:25	Chicago 95Th & Dan Ryan	No tags
	Bus	07:40	Pittsburgh Intermodal Station	13h 25m	20:05	Downtown Greyhound Station	No tags

Next departures from Pittsburgh to Chicago on 26 November
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	19:45	Pittsburgh Intermodal Station	11h 25m	06:10	Downtown Greyhound Station	Cheapest
	Bus	00:40	Pittsburgh Intermodal Station	10h 20m	10:00	Downtown Greyhound Station	Fastest
	Bus	01:35	Pittsburgh Intermodal Station	14h	14:35	Downtown Greyhound Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	00:40	Pittsburgh Intermodal Station	13h 45m	13:25	Chicago 95Th & Dan Ryan	No tags
	Bus	19:45	Pittsburgh Intermodal Station	10h 55m	05:40	Chicago 95Th & Dan Ryan	No tags

Next departures from Pittsburgh to Chicago on 27 November
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	07:40	Pittsburgh Intermodal Station	13h 25m	20:05	Downtown Greyhound Station	Cheapest
	Bus	00:40	Pittsburgh Intermodal Station	10h 20m	10:00	Downtown Greyhound Station	Fastest
	Bus	01:35	Pittsburgh Intermodal Station	14h	14:35	Downtown Greyhound Station	No tags
	Bus	19:45	Pittsburgh Intermodal Station	11h 25m	06:10	Downtown Greyhound Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	00:40	Pittsburgh Intermodal Station	13h 45m	13:25	Chicago 95Th & Dan Ryan	No tags

Last refresh of the prices: Today at 08:24 EST.

Compare 2 ways to travel from Pittsburgh to Chicago

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach Chicago. The journey takes about 9 hours 46 minutes and with fares starting at just £41, it presents an excellent value for a comfortable ride.

1train per day

9h 46mAverage duration

409 milesDistance

60kgCO₂ emissions

	Average price	Average duration	CO₂ emissions	Actions
Bus	Average price£44 - £172	Average duration13h 35m	CO₂ emissions 16kg CO₂e
Train	Average price£41 - £148	Average duration9h 46m	CO₂ emissions 60kg CO₂e

Compare bus companies

Greyhound

3.5/587,385 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

WiFi2.4

FlixBus

3.5/511,381 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

WiFi2.7

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Where are the popular stops in Pittsburgh and Chicago?

Stops in Pittsburgh

A
Intermodal Station
55 11th St, Pittsburgh, PA 15222, USA
Visit page
B
Sennott Square
201 S Bouquet St, Pittsburgh, PA 15213, USA

Stops in Chicago

A
Downtown Greyhound Station
630 W Harrison St, Chicago, IL 60607, USA
Visit page
B
Chicago O'Hare International Airport
Visit page
C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA
D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA
E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA
F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA

Frequently asked questions about travelling by bus from Pittsburgh to Chicago

What's the distance between Pittsburgh and Chicago by coach?
The journey from Pittsburgh to Chicago by coach covers an approximate distance of 410 miles (661 km).
What is the best way to go from Pittsburgh to Chicago without flying?
You can choose the coach to travel this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

18/11

£70

19/11

£72

Today

£72

21/11

£72

22/11

£70

23/11

£77

24/11

£65

25/11

£77

The cheapest trip from Pittsburgh to Chicago was searched and found on 24 Nov 2025 with a price of £65

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pittsburgh to Chicago as early as possible.

You can expect to pay from £65 to £195 for a bus ticket from Pittsburgh to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at £65, which is on 2025-11-24.

Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.