Find coaches from Indianapolis to Buffalo, NY

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Today25 Jun
from US$99
Tomorrow26 Jun
from US$100
Fri27 Jun
from US$106
Sat28 Jun
from US$117
Sun29 Jun
Mon30 Jun
from US$104
Tue1 Jul
from US$103
Wed2 Jul

Next departures to Buffalo

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 26 June at
    Departure city: Indianapolis
    Departure location: Downtown Transit Center
    Arrival time: 27 June at
    Destination city: Buffalo
    Destination location: Niagara Frontier Transportation Authority
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 26 June at
    Departure city: Indianapolis
    Departure location: Downtown Transit Center
    Arrival time: 26 June at
    Destination city: Buffalo
    Destination location: Niagara Frontier Transportation Authority
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 26 June at
    Departure city: Indianapolis
    Departure location: Greyhound Amtrak Station
    Arrival time: 27 June at
    Destination city: Buffalo
    Destination location: Depew Station
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • Departure time: 26 June at
    Departure city: Indianapolis
    Departure location: Indianapolis Bus Station
    Arrival time: 27 June at
    Destination city: Buffalo
    Destination location: Niagara Frontier Transportation Authority
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 26 June at
    Departure city: Indianapolis
    Departure location: Downtown Transit Center
    Arrival time: 26 June at
    Destination city: Buffalo
    Destination location: Niagara Frontier Transportation Authority
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to travel from Indianapolis to Buffalo

Bus
Average priceUS$96 - US$239Average duration17h 45m
18kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average priceUS$175 - US$911Average duration1d 2h
65kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Indianapolis to Buffalo

Among the sustainable travel choices, the bus stands out as a good way to reach Buffalo. The journey takes about 17 hours 45 minutes and with fares starting at just US$96, it presents an excellent value for a comfortable ride.

5bus per day
17h 45mAverage duration
US$96Cheapest ticket
18kgCO₂ emissions

Bus Indianapolis to Buffalo: Trip Overview

Average ticket priceUS$121
Average bus trip duration17h 45m
Number of daily buses4.642857142857142
Earliest bus departure00:20
Distance434 miles
Latest bus departure23:30

Indianapolis to Buffalo Bus

With Busbud, comparing and booking tickets for a bus from Indianapolis to Buffalo is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Indianapolis to Buffalo.

Discover how much the bus trip from Indianapolis to Buffalo will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Indianapolis - Buffalo, NY

  1. How far is Buffalo from Indianapolis by coach?

    The distance between Indianapolis and Buffalo by coach is approximately 435 miles (701 km).

  2. Is there a way to reach Buffalo from Indianapolis without flying?

    You have the option to select the coach for your journey on this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
23/06
No data
24/06
No data
Today
US$95
26/06
US$121
27/06
US$113
28/06
US$109
29/06
US$122
30/06
US$126
busbud logoThe cheapest trip from Indianapolis to Buffalo was searched and found on 25 Jun 2025 with a price of US$95

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to Buffalo as early as possible.

You can expect to pay from US$95 to US$1,498 for a bus ticket from Indianapolis to Buffalo based on the last 2 days. You can expect to find the cheapest price for the trip at US$109, which is on 2025-06-28.

Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Indianapolis to Buffalo.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Indianapolis to Buffalo.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Indianapolis to Buffalo will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Indianapolis to Buffalo while indulging in miles on end of beautiful scenic views.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

What's the cheapest way to go from Indianapolis to Buffalo?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Indianapolis by bus?

Bus from Indianapolis to Buffalo

You can also go to Buffalo by train

Train from Indianapolis to Buffalo

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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