Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Bus station | 1116 Woodruff Rd | CheapestFastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Florence, SC | 1116 Woodruff Rd | No tags |
Last refresh of the prices: Last Monday at 10:49 EST.
Compare 2 ways to travel from Florence to Greenville
Among the sustainable travel choices, the Bus stands out as a good way to reach Greenville. The journey takes about 10 hours 45 minutes and with fares starting at just £83, it presents an excellent value for a comfortable ride.
Where are the popular stops in Florence and Greenville?
Stops in Florence
- A619 S Irby St, Florence, SC 29501, USA
- B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Compare bus companies
Based on 12055 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at £93
Frequently asked questions about travelling by bus from Florence, SC, US to Greenville, SC
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Florence to Greenville?
The cheapest coach tickets from Florence to Greenville start from £83. The average price for this route is around £102. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Florence to Greenville?
The average bus journey time from Florence to Greenville is 10h 45m, covering a distance of 151 miles. The fastest bus can take you there in 5h 40m and is operated by FlixBus.
Which bus companies service the Florence to Greenville route?
Several major bus companies operate on this route with 2 buses available per day.
What is the earliest and latest departure time for the bus from Florence to Greenville?
The earliest bus departs from Florence to Greenville at 00:05. And the latest bus departs at 13:45.
What are the CO₂ emissions for the bus trip from Florence to Greenville?
A bus journey from Florence to Greenville produces an estimated 6 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Florence, SC, US to Greenville, SC was searched and found on 19 Jan 2026 with a price of £92To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Greenville, SC as early as possible.
You can expect to pay from £92 to £92 for a bus ticket from Florence, SC, US to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at £92, which is on 2026-01-19.
What's the cheapest way to go from Florence, SC, US to Greenville, SC?
The Bus is the cheapest travel choice for this destination
