Based on 87393 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at £35
Greyhound Lines, Inc. Des Moines Chicago recent customer reviews
I was unaware the ticket process was through a 3rd party. Not recomended.
Based on 759 reviews, the company was rated 3.9 stars on Busbud. Travellers were especially satisfied with the temperature and the seats but often complained with the Wi-Fi. Jefferson Lines ticket prices on this trip start at £49
Based on 20 reviews, the company was rated 4.2 stars on Busbud. Travellers were especially satisfied with the staff and the timeliness but often complained with the ticket access. Burlington Trailways ticket prices on this trip start at £127
Frequently asked questions about travelling by bus from Des Moines to Chicago
What's the distance between Des Moines and Chicago by coach?
The journey from Des Moines to Chicago by coach covers an approximate distance of 308 miles (496 km).
What is the best way to go from Des Moines to Chicago without flying?
To travel from Des Moines to Chicago without flying, you can take the coaches. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You also have the option of utilising carpooling services.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
21/11
£123
22/11
£123
Today
£123
24/11
£50
25/11
£65
26/11
£63
27/11
£37
28/11
£37
The cheapest trip from Des Moines to Chicago was searched and found on 27 Nov 2025 with a price of £37
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Des Moines to Chicago as early as possible.
You can expect to pay from £37 to £123 for a bus ticket from Des Moines to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at £37, which is on 2025-11-27.
Usually Jefferson Lines, Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
The cheapest trip from Des Moines to Chicago was searched and found on 27 Nov 2025 with a price of £37
