Next departures from Chicago to San Antonio on 26 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
Chicago 95Th & Dan Ryan
Pearl District
Cheapest
Greyhound Lines, Inc. + Greyhound Lines Mexico
Bus
Downtown Greyhound Station
San Antonio Bus Station
Fastest
Greyhound Lines, Inc. + FlixBus
Bus
Downtown Greyhound Station
Pearl District
No tags
Greyhound Lines, Inc. + Greyhound Lines Mexico
Bus
537-517 W. Jackson Blvd
San Antonio Bus Station
No tags
FlixBus + Greyhound Lines, Inc. + Valley Transit
Bus
Chicago 95Th & Dan Ryan
San Antonio Bus Station
No tags
Next departures from Chicago to San Antonio on 27 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Chicago 95Th & Dan Ryan
Pearl District
Cheapest
Tornado Bus + Expreso
Bus
Chicago, IL
Tornado I-35
Fastest
FlixBus + Greyhound Lines, Inc. + Valley Transit
Bus
Downtown Greyhound Station
San Antonio Bus Station
No tags
Greyhound Lines, Inc. + Greyhound Lines Mexico
Bus
Downtown Greyhound Station
San Antonio Bus Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Downtown Greyhound Station
Pearl District
No tags
Next departures from Chicago to San Antonio on 28 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc. + Valley Transit
Bus
Chicago 95Th & Dan Ryan
San Antonio Bus Station
Cheapest
Tornado Bus + Expreso
Bus
Chicago, IL
Tornado I-35
Fastest
FlixBus + Greyhound Lines, Inc. + Valley Transit
Bus
Downtown Greyhound Station
San Antonio Bus Station
No tags
Greyhound Lines, Inc. + Greyhound Lines Mexico
Bus
Downtown Greyhound Station
San Antonio Bus Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Downtown Greyhound Station
Pearl District
No tags
Next departures from Chicago to San Antonio on 29 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Chicago, IL
Tornado I-35
Cheapest
Tornado Bus + Expreso
Bus
Chicago, IL
Tornado I-35
Fastest
FlixBus + Greyhound Lines, Inc. + Valley Transit
Bus
Downtown Greyhound Station
San Antonio Bus Station
No tags
Greyhound Lines, Inc. + Greyhound Lines Mexico
Bus
Downtown Greyhound Station
San Antonio Bus Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Downtown Greyhound Station
Pearl District
No tags
Next departures from Chicago to San Antonio on 30 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc. + Valley Transit
Bus
Chicago 95Th & Dan Ryan
San Antonio Bus Station
Cheapest
Tornado Bus + Expreso
Bus
Chicago, IL
Tornado I-35
Fastest
FlixBus + Greyhound Lines, Inc. + Valley Transit
Bus
Downtown Greyhound Station
San Antonio Bus Station
No tags
Greyhound Lines, Inc. + Greyhound Lines Mexico
Bus
Downtown Greyhound Station
San Antonio Bus Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Downtown Greyhound Station
Pearl District
No tags
Next departures from Chicago to San Antonio on 1 December
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc. + Valley Transit
Bus
Chicago 95Th & Dan Ryan
San Antonio Bus Station
Cheapest
Tornado Bus + Expreso
Bus
Chicago, IL
Tornado I-35
Fastest
FlixBus + Greyhound Lines, Inc. + Valley Transit
Bus
Downtown Greyhound Station
San Antonio Bus Station
No tags
Greyhound Lines, Inc. + Greyhound Lines Mexico
Bus
Downtown Greyhound Station
San Antonio Bus Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Downtown Greyhound Station
Pearl District
No tags
Next departures from Chicago to San Antonio on 2 December
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc. + Valley Transit
Bus
Chicago 95Th & Dan Ryan
San Antonio Bus Station
Cheapest
Tornado Bus + Expreso
Bus
Chicago, IL
Tornado I-35
Fastest
Greyhound Lines, Inc. + Valley Transit
Bus
Downtown Greyhound Station
San Antonio Bus Station
No tags
Greyhound Lines, Inc. + Greyhound Lines Mexico
Bus
Downtown Greyhound Station
San Antonio Bus Station
No tags
FlixBus + Greyhound Lines, Inc. + Greyhound Lines Mexico
Bus
Chicago 95Th & Dan Ryan
San Antonio Bus Station
No tags
Next departures from Chicago to San Antonio on 3 December
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Chicago 95Th & Dan Ryan
Pearl District
Cheapest
Tornado Bus + Expreso
Bus
Chicago, IL
Tornado I-35
Fastest
Greyhound Lines, Inc. + Valley Transit
Bus
Downtown Greyhound Station
San Antonio Bus Station
No tags
Greyhound Lines, Inc. + Greyhound Lines Mexico
Bus
Downtown Greyhound Station
San Antonio Bus Station
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Downtown Greyhound Station
Pearl District
No tags
Last refresh of the prices: Yesterday at 21:08 CST.
Compare 2 ways to travel from Chicago to San Antonio
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as a good way to reach San Antonio. The journey takes about 1 day, 3 hours 10 minutes and with fares starting at just £80, it presents an excellent value for a comfortable ride.
Based on 156 reviews, the company was rated 3.1 stars on Busbud. Travellers were especially satisfied with the value for money and the ticket access but often complained with the timeliness. Tornado Bus ticket prices on this trip start at £201
Based on 87397 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at £67
Based on 11451 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at £67
Frequently asked questions about travelling by bus from Chicago to San Antonio, US
How far is San Antonio from Chicago by coach?
The distance between Chicago and San Antonio by coach is approximately 1050 miles (1693 km).
What is the best way to go from Chicago to San Antonio without flying?
You can choose the coach to travel this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You also have the option of utilising carpooling services.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
24/11
£215
25/11
£215
Today
£215
27/11
£215
28/11
£215
29/11
£215
30/11
£215
01/12
£215
The cheapest trip from Chicago to San Antonio, US was searched and found on 24 Nov 2025 with a price of £215
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to San Antonio, US as early as possible.
You can expect to pay from £215 to £226 for a bus ticket from Chicago to San Antonio, US based on the last 2 days. You can expect to find the cheapest price for the trip at £215, which is on 2025-11-27.