Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | 4565 Gaynor Ave, North Charleston | Pittsburgh Intermodal Station | CheapestFastest |
Last refresh of the prices: Yesterday at 10:16 EST.
Compare 2 ways to travel from Charleston to Pittsburgh
Among the sustainable travel choices, the bus stands out as a good way to reach Pittsburgh. The journey takes about 22 hours 40 minutes and with fares starting at just £74, it presents an excellent value for a comfortable ride.
Where are the popular stops in Charleston and Pittsburgh?
Stops in Charleston
- A
Charleston Bus Station
3610 Dorchester Rd, North Charleston, SC 29405
Stops in Pittsburgh
- A55 11th St, Pittsburgh, PA 15222, USA
- B
Sennott Square
201 S Bouquet St, Pittsburgh, PA 15213, USA
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Frequently asked questions about travelling by bus from Charleston, SC, US to Pittsburgh
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Charleston to Pittsburgh?
The cheapest coach tickets from Charleston to Pittsburgh start from £74. The average price for this route is around £120. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Charleston to Pittsburgh?
The average bus journey time from Charleston to Pittsburgh is 22h 40m, covering a distance of 522 miles. The fastest bus can take you there in 22h 40m and is operated by Greyhound.
Which bus companies service the Charleston to Pittsburgh route?
What is the earliest and latest departure time for the bus from Charleston to Pittsburgh?
The earliest bus departs from Charleston to Pittsburgh at 11:15. And the latest bus departs at 15:15.
What are the CO₂ emissions for the bus trip from Charleston to Pittsburgh?
A bus journey from Charleston to Pittsburgh produces an estimated 21 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Charleston to Pittsburgh?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11380 reviews.
Which company has the best Wi-Fi from Charleston to Pittsburgh?
Based on Busbud reviews, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Charleston to Pittsburgh?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Charleston to Pittsburgh?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Charleston, SC, US to Pittsburgh was searched and found on 28 Nov 2025 with a price of £126To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charleston, SC, US to Pittsburgh as early as possible.
You can expect to pay from £126 to £144 for a bus ticket from Charleston, SC, US to Pittsburgh based on the last 2 days. You can expect to find the cheapest price for the trip at £144, which is on 2025-12-02.
What's the cheapest way to go from Charleston, SC, US to Pittsburgh?
The bus is the cheapest travel choice for this destination
