Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Boston (South Station) | Des Moines | Cheapest | ||||
 | Bus | Boston (South Station) | Des Moines | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Brookline | Des Moines | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Brookline | Des Moines | No tags |
Last refresh of the prices: Yesterday at 14:50 EST.
Get from Boston to Des Moines
The journey takes about 1 day, 21 hours 45 minutes, and with fares starting at just £91, it presents an excellent value for a comfortable ride.
Where are the popular stops in Boston and Des Moines?
Stops in Boston
- A145 Dartmouth St, Boston, MA 02116, USA
- B100 Legends Way, Boston, MA 02114, USA
- C
Copley Square
115-127 St James Ave, Boston, MA 02116, USA - D
Prudential MBTA Station
220 Huntington Ave, Boston, MA 02115, USA - E
Copley MBTA Station
650 Boylston St, Boston, MA 02116, USA - F
Long Wharf
66 Long Wharf, Boston, MA 02110, USA
Stops in Des Moines
- A
Jefferson/Trailways Depot
1501 2nd Ave North, Des Moines, IA 50314 - B
1514 East Grand Ave
1514 East Grand Avenue,, Des Moins, IA, 50316
Compare bus companies
Frequently asked questions about travelling by bus from Boston, MA, US to Des Moines
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Boston to Des Moines?
The cheapest coach tickets from Boston to Des Moines start from £91. The average price for this route is around £203. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Boston to Des Moines?
The average bus journey time from Boston to Des Moines is 1d 21h, covering a distance of 1150 miles. The fastest bus can take you there in 1d 10h and is operated by Greyhound.
Which bus companies service the Boston to Des Moines route?
What is the earliest and latest departure time for the bus from Boston to Des Moines?
The earliest bus departs from Boston to Des Moines at 01:30. And the latest bus departs at 21:50.
What are the CO₂ emissions for the bus trip from Boston to Des Moines?
A bus journey from Boston to Des Moines produces an estimated 46 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Boston to Des Moines?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87435 reviews.
Which company has the best Wi-Fi from Boston to Des Moines?
Based on Busbud reviews, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Boston to Des Moines?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Boston to Des Moines?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Boston, MA, US to Des Moines was searched and found on 25 Dec 2025 with a price of £175To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston, MA, US to Des Moines as early as possible.
You can expect to pay from £175 to £278 for a bus ticket from Boston, MA, US to Des Moines based on the last 2 days. You can expect to find the cheapest price for the trip at £213, which is on 2025-12-29.
