Next train departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Santander | Madrid-Chamartin | CheapestFastest | ||||
| Train | Santander | Madrid-Chamartin | No tags | ||||
| Train | Santander | Madrid-Chamartin | No tags |
Last refresh of the prices: Today at 2:06 PM CET.
Compare 3 ways to go from Santander to Madrid
Among the sustainable travel choices, the carpool stands out as a good way to reach Madrid. The journey takes about 4 hours 20 minutes, and with fares starting at just $29, it presents an excellent value for a comfortable ride.
Where are the popular train stations and stops in Santander and Madrid?
Santander
- ACalle Navas de Tolosa, 2, 39002 Santander, Cantabria, Spain
Madrid
- AC. de la Hiedra, 5, 28036 Madrid, Spain
- BMadrid Atocha railway station, Plaza del Emperador Carlos V, 28045 Madrid, Spain
- CPríncipe Pío, 28008 Madrid, Spain
- E
Nuevos Ministerios
Estación de Nuevos Ministerios, 28046 Madrid, Spain
Train companies
Based on 916 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the staff and the seats but often complained with the WiFi. Renfe ticket prices on this trip start at $48
Frequently asked questions about travelling from Santander to Madrid by train
How much does a cheap train ticket from Santander to Madrid cost?
The average train ticket price from Santander to Madrid is $78. The best way to find cheap train tickets from Santander to Madrid is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the trip from Santander to Madrid?
A train trip between Santander and Madrid is around 4h 16m, although the fastest train will take about 4h 16m. This is the time it takes to travel the 340 km that separates the two cities.
How many daily trains are there between Santander and Madrid?
The number of trains from Santander to Madrid can differ depending on the day of the week. On average, there is 1. Some trains are direct while others have layovers. Simplify your train trip from Santander to Madrid by comparing and selecting the train that fits your travel style and budget on Busbud.
Which train companies travel from Santander to Madrid?
When taking the train from Santander to Madrid, you can travel comfortably and safely with Renfe.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santander to Madrid was searched and found on Nov 24, 2025 with a price of $61To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Santander to Madrid, as early as possible.
You can expect to pay from $61 to $109 for a train ticket from Santander to Madrid based on the last 2 days. You can expect to find the cheapest price for the trip at $61 which is on 2025-11-24.
