Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Wilmington Bus Station | Roanoke Bus Stop | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Newark (DE) | Roanoke Bus Stop | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Delaware Rest Stop S | Roanoke Bus Stop | No tags |
Last refresh of the prices: Last Saturday at 9:07 PM EST.
Compare 2 ways to go from Wilmington to Roanoke
Among the sustainable travel choices, the train stands out as a good way to reach Roanoke. The journey takes about 7 hours 19 minutes, and with fares starting at just $70, it presents an excellent value for a comfortable ride.
Where are the popular stops in Wilmington and Roanoke?
Stops in Wilmington
- AWilmington Bus Station, 101 N French St, Wilmington, DE 19801, USA
- B100 French St, Wilmington, DE 19801, USA
- C
Wilmington Bus Stop
101 N French , Wilmington, DE 19801
Stops in Roanoke
- AExit 140 (Park and Ride), Virginia 24153, USA
Compare bus companies
Based on 87393 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $53
Frequently asked questions about travelling from Wilmington, DE to Roanoke by bus
What is the travel distance from Wilmington to Roanoke?
The distance between Wilmington and Roanoke is approximately 470 km (292 miles).
What are the departure and arrival locations for buses traveling from Wilmington to Roanoke?
Buses departing from Wilmington Bus Station in Wilmington will take you to Salem - Exit 140 Park & Ride in Roanoke.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Wilmington, DE to Roanoke was searched and found on Nov 26, 2025 with a price of $114To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Wilmington, DE to Roanoke, as early as possible.
You can expect to pay from $114 to $174 for a bus ticket from Wilmington, DE to Roanoke based on the last 2 days. You can expect to find the cheapest price for the trip at $114 which is on 2025-11-26.
What's the cheapest way to go from Wilmington, DE to Roanoke?
The bus is the cheapest travel choice for this destination
