Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Tri-Rail & Greyhound | 1116 Woodruff Rd | Cheapest | ||||
 | Bus | Tri-Rail & Greyhound | 1116 Woodruff Rd | Fastest | ||||
 | Bus | Tri-Rail & Greyhound | 1116 Woodruff Rd | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Tri-Rail & Greyhound | 1116 Woodruff Rd | No tags |
Last refresh of the prices: Yesterday at 3:13 PM EST.
Compare 2 ways to go from West Palm Beach to Greenville
Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 19 hours, and with fares starting at just $140, it presents an excellent value for a comfortable ride.
Where are the popular stops in West Palm Beach and Greenville?
Stops in West Palm Beach
- A205 S Tamarind Ave, West Palm Beach, FL 33401
- BHeading North go to North-bound side of building., Heading South go to South-bound side of building., Mile Marker 94 Florida's Turnpike, West Palm Beach, FL 33413, USA
- C
Okeechobee Rd & I-95
Shell Station , 1850 Okeechobee Blvd, West Palm Beach, FL 33409, USA - D
Lake Worth Service Plaza
8195 Lake Worth Rd, Lake Worth FL 33467 USA, FLORIDAS TURNPIKE MILE 94 - E
Vedado
El Barrio Grocery, 3905 Lake Ave, West Palm Beach, FL 33405, USA
Stops in Greenville
- A
Guadalajara Supermarket Bus Stop
2803 White Horse Rd, Greenville, SC 29611 - B
Greenville Bus Station
9 Hendrix DR, Greenville, SC 29607
Compare bus companies
Frequently asked questions about travelling from West Palm Beach to Greenville, SC by bus
What is the travel distance from West Palm Beach to Greenville?
The distance between West Palm Beach and Greenville is approximately 933 km (579 miles).
What are the departure and arrival locations for buses traveling from West Palm Beach to Greenville?
Buses departing from Tri-Rail & Greyhound in West Palm Beach will take you to Guadalajara Supermarket Bus Stop in Greenville.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from West Palm Beach to Greenville, SC was searched and found on Nov 24, 2025 with a price of $197To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from West Palm Beach to Greenville, SC, as early as possible.
You can expect to pay from $197 to $382 for a bus ticket from West Palm Beach to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at $207 which is on 2025-12-01.
What's the cheapest way to go from West Palm Beach to Greenville, SC?
The bus is the cheapest travel choice for this destination
