Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Gateway Station | Louisville, KY | Cheapest | ||||
 | Bus | Gateway Station | Louisville, KY | Fastest | ||||
| Bus | Gateway Station | Louisville, KY | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Gateway Station | Louisville, KY | No tags | ||||
| Bus | Gateway Station | Louisville, KY | No tags |
Last refresh of the prices: Yesterday at 5:19 AM CST.
Get from St. Louis to Louisville
The journey takes about 10 hours 25 minutes, and with fares starting at just $69, it presents an excellent value for a comfortable ride.
Where are the popular stops in St. Louis and Louisville?
Stops in Louisville
- A
Louisville Greyhound Bus Station
720 W Muhammad Ali Blvd, Louisville, KY 40203
Compare bus companies
Frequently asked questions about travelling from St. Louis to Louisville by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from St. Louis to Louisville?
The cheapest bus tickets from St. Louis to Louisville start from $69. The average price for this route is around $115. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from St. Louis to Louisville?
The average bus travel time from St. Louis to Louisville is 10h 25m, covering a distance of 389 km. The quickest bus can get you there in 7h 5m and is operated by Greyhound.
Which bus companies service the St. Louis to Louisville route?
What are the earliest and latest departure times for the bus from St. Louis to Louisville?
The earliest bus departs from St. Louis to Louisville at 2:00am. And the latest bus departs at 11:30pm.
What are the CO₂ emissions for the bus trip from St. Louis to Louisville?
A bus trip from St. Louis to Louisville generates an estimated 10 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from St. Louis to Louisville?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87463 reviews.
Which bus company has the best Wi-Fi from St. Louis to Louisville?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from St. Louis to Louisville?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from St. Louis to Louisville?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from St. Louis to Louisville was searched and found on Jan 12, 2026 with a price of $68To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Louisville, as early as possible.
You can expect to pay from $68 to $118 for a bus ticket from St. Louis to Louisville based on the last 2 days. You can expect to find the cheapest price for the trip at $68 which is on 2026-01-12.
