Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Terminal Sur | Terminal de Autobuses de San Nicolas | CheapestFastest | ||||
| Bus | Terminal Sur | Terminal de Autobuses de San Nicolas | No tags | ||||
| Bus | Terminal Sur | Terminal de Autobuses de San Nicolas | No tags | ||||
| Bus | Terminal Sur | Terminal de Autobuses de San Nicolas | No tags | ||||
| Bus | Terminal Sur | Terminal de Autobuses de San Nicolas | No tags |
Last refresh of the prices: Last Sunday at 9:58 PM -03.
Get from Santiago to San Nicolás
The journey takes about 4 hours 16 minutes, and with fares starting at just $15, it presents an excellent value for a comfortable ride.
Where are the popular stops in Santiago and San Nicolás?
Stops in Santiago
- ASantiago - Av Libertador Bernardo O'Higgins 3850, Santiago, Estación Central, Región Metropolitana, Chile
- B
San Borja
San Francisco de Borja 199-225, Santiago, Estación Central, Región Metropolitana, Chile - CTucapel Jiménez 21, 8340528 Santiago, Región Metropolitana, Chile
- DPdte. Riesco 6391-6399, Las Condes, Región Metropolitana, Chile
- EAv. Gral. Oscar Bonilla 418, Lo Prado, Región Metropolitana, Chile
- F
Santiago
Juan Esteban Montero 5688, Las Condes, Las Condes, Región Metropolitana, Chile
Stops in San Nicolás
- A
Terminal de Autobuses de San Nicolas
N-50 312-448, San Nicolás, Región del Bío Bío, Chile
Compare bus companies
Based on 157 reviews, the company was rated 3.8 stars on Busbud. Travellers were especially satisfied with the cleanliness and the ticket access but often complained with the WiFi. Eme Bus ticket prices on this trip start at $15
Frequently asked questions about travelling from Santiago, CL to San Nicolás, CL by bus
What is the travel distance from Santiago to San Nicolás?
The distance between Santiago and San Nicolás is around 374 km (232 miles).
What are the departure and arrival locations for buses traveling from Santiago to San Nicolás?
Buses traveling this route start their trip at Terminal Sur, in Santiago, and end it at Terminal de Autobuses de San Nicolas, in San Nicolás.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santiago, CL to San Nicolás, CL was searched and found on Nov 24, 2025 with a price of $15To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santiago, CL to San Nicolás, CL, as early as possible.
You can expect to pay from $15 to $29 for a bus ticket from Santiago, CL to San Nicolás, CL based on the last 2 days. You can expect to find the cheapest price for the trip at $15 which is on 2025-11-27.
