Bus from Santiago, CL to Pueblo Seco: Tickets & Schedules

Previously seen trips

Next departures for Santiago to Pueblo Seco on November 26
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
buses TranSantinBus
Terminal Sur
Parada Pueblo SecoNo tags
Buses Jet SurBus
Terminal Sur
Pueblo SecoNo tags
buses TranSantinBus
Terminal Sur
Parada Pueblo SecoNo tags
buses TranSantinBus
Terminal Sur
Parada Pueblo SecoNo tags
Buses Jet SurBus
Terminal Sur
Pueblo SecoNo tags

Get from Santiago to Pueblo Seco

This route is served by bus only

The journey takes about 5 hours 30 minutes, and with fares starting at just $26, it presents an excellent value for a comfortable ride.

2bus per day
5h 30mAverage Duration
402 kmDistance
10kgCO₂ emissions

Frequently asked questions about travelling from Santiago, CL to Pueblo Seco by bus

  1. What is the distance between Santiago and Pueblo Seco?

    It's about 410 km (254 miles) from Santiago to Pueblo Seco.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11-24
No data
11-25
No data
Today
$21
11-27
No data
11-28
No data
11-29
No data
11-30
No data
12-01
No data
busbud logoThe cheapest trip from Santiago, CL to Pueblo Seco was searched and found on Nov 26, 2025 with a price of $21

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santiago, CL to Pueblo Seco, as early as possible.

People from around the world trust Busbud