Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Estación Terminal de Ómnibius, Santa Fe | Terminal de Ómnibus de Villa Mercedes | Cheapest | ||||
 | Bus | Estación Terminal de Ómnibius, Santa Fe | Terminal de Ómnibus de Villa Mercedes | Fastest | ||||
| Bus | Estación Terminal de Ómnibius, Santa Fe | Terminal de Ómnibus de Villa Mercedes | No tags | ||||
| Bus | Estación Terminal de Ómnibius, Santa Fe | Terminal de Ómnibus de Villa Mercedes | No tags | ||||
 | Bus | Estación Terminal de Ómnibius, Santa Fe | Terminal de Ómnibus de Villa Mercedes | No tags |
Last refresh of the prices: Last Wednesday at 12:16 PM -03.
Get from Santa Fe to Villa Mercedes
The journey takes about 9 hours 25 minutes, and with fares starting at just $50, it presents an excellent value for a comfortable ride.
Where are the popular stops in Santa Fe and Villa Mercedes?
Stops in Santa Fe
- A
Estación Terminal de Ómnibius, Santa Fe
Estación Terminal de Onmibus Belgrano 2900 , S3000GCH Santa Fe, Argentina
Stops in Villa Mercedes
- A
Terminal de Ómnibus de Villa Mercedes
Avenida 25 de Mayo, 1462 (esq Hilario Cuadros), 5730 Villa Mercedes
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Frequently asked questions about travelling from Santa Fe, AR to Villa Mercedes by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Santa Fe to Villa Mercedes?
The cheapest bus tickets from Santa Fe to Villa Mercedes start from $50. The average price for this route is around $67. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Santa Fe to Villa Mercedes?
The average bus travel time from Santa Fe to Villa Mercedes is 9h 25m, covering a distance of 500 km. The quickest bus can get you there in 9h 10m and is operated by Flechabus.
Which bus companies service the Santa Fe to Villa Mercedes route?
Several major bus companies operate on this route with 3 buses available per day, including services from 20 de Junio, Andesmar, Flechabus.
What are the earliest and latest departure times for the bus from Santa Fe to Villa Mercedes?
The earliest bus departs from Santa Fe to Villa Mercedes at 2:00am. And the latest bus departs at 9:00pm.
What are the CO₂ emissions for the bus trip from Santa Fe to Villa Mercedes?
A bus trip from Santa Fe to Villa Mercedes generates an estimated 12 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Santa Fe to Villa Mercedes?
According to Busbud customers, the highest-rated bus company on this route is 20 de Junio, with an average rating of 4.0 out of 5 stars based on 598 reviews.
Which bus company has the best Wi-Fi from Santa Fe to Villa Mercedes?
Based on Busbud reviews, the bus company 20 de Junio has the highest Wi-Fi rating with a score of 2.3.
Which bus company has the best on-time performance from Santa Fe to Villa Mercedes?
According to Busbud traveller reviews, the most punctual bus company on this route is 20 de Junio, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Santa Fe to Villa Mercedes?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is 20 de Junio, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santa Fe, AR to Villa Mercedes was searched and found on Jan 28, 2026 with a price of $50To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Fe, AR to Villa Mercedes, as early as possible.
You can expect to pay from $50 to $93 for a bus ticket from Santa Fe, AR to Villa Mercedes based on the last 2 days. You can expect to find the cheapest price for the trip at $50 which is on 2026-01-28.
