Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | AMTRAK Station | Mission St & Fremont St | Cheapest | |||||
| Cal Poly Vista Grande Dining Complex | Mission St & Fremont St | Fastest |
Last refresh of the prices: Today at 8:11 AM PST.
Get from San Luis Obispo to San Francisco
The journey takes about 4 hours 35 minutes, and with fares starting at just $23, it presents an excellent value for a comfortable ride.
Where are the popular stops in San Luis Obispo and San Francisco?
Stops in San Luis Obispo
- A1730 Santa Rosa St, San Luis Obispo, CA 93401, USA
- B
San Luis Obispo Bus Stop
1460 Calle Joaquin, San Luis Obispo, CA 93405, USA
Stops in San Francisco
- A
Hyde/Beach (Fisherman's Wharf)
700 Beach Street, San Francisco, CA 94109, USA - B
Powell Station
25 Cyril Magnin St , San Francisco, CA 94102-2812 - C
Union Square Hilton
255 Mason St,, San Francisco, CA 94102-2114 - D
San Francisco Greyhound Station
200 Folsom St, San Francisco, CA 94105 - E
444 Townsend St.
444 Townsend St, San Francisco, CA 94107, USA
Compare bus companies
Frequently asked questions about travelling from San Luis Obispo to San Francisco, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from San Luis Obispo to San Francisco?
The cheapest bus tickets from San Luis Obispo to San Francisco start from $23. The average price for this route is around $82. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from San Luis Obispo to San Francisco?
The average bus travel time from San Luis Obispo to San Francisco is 4h 35m, covering a distance of 319 km. The quickest bus can get you there in 4h 10m and is operated by FlixBus.
Which bus companies service the San Luis Obispo to San Francisco route?
What are the earliest and latest departure times for the bus from San Luis Obispo to San Francisco?
The earliest bus departs from San Luis Obispo to San Francisco at 12:30am. And the latest bus departs at 4:35pm.
What are the CO₂ emissions for the bus trip from San Luis Obispo to San Francisco?
A bus trip from San Luis Obispo to San Francisco generates an estimated 8 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from San Luis Obispo to San Francisco?
According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5597 reviews.
Which bus company has the best Wi-Fi from San Luis Obispo to San Francisco?
Based on Busbud reviews, the bus company Amtrak has the highest Wi-Fi rating with a score of 3.6.
Which bus company has the best on-time performance from San Luis Obispo to San Francisco?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from San Luis Obispo to San Francisco?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Luis Obispo to San Francisco, US was searched and found on Nov 28, 2025 with a price of $117To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Luis Obispo to San Francisco, US, as early as possible.
You can expect to pay from $117 to $174 for a bus ticket from San Luis Obispo to San Francisco, US based on the last 2 days. You can expect to find the cheapest price for the trip at $122 which is on 2025-12-04.
