Bus Tickets from San Diego (CA), US to Tampa

Find affordable bus tickets from San Diego (CA), US to Tampa with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayJun 1
TomorrowJun 2
from US$629
TueJun 3
WedJun 4
ThuJun 5
FriJun 6
SatJun 7
SunJun 8

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: June 2 at
    Departure city: San Diego
    Departure location: UCSD Health La Jolla Station
    Arrival time: June 5 at
    Destination city: Tampa
    Destination location: Tampa Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: June 2 at
    Departure city: San Diego
    Departure location: UCSD Health La Jolla Station
    Arrival time: June 5 at
    Destination city: Tampa
    Destination location: Tampa Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 2 at
    Departure city: San Diego
    Departure location: San Diego (Old Town-FlixBus)
    Arrival time: June 5 at
    Destination city: Tampa
    Destination location: Tampa Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 2 at
    Departure city: San Diego
    Departure location: Greyhound Bus Stop
    Arrival time: June 5 at
    Destination city: Tampa
    Destination location: Tampa Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 2 at
    Departure city: San Diego
    Departure location: San Diego (Old Town-FlixBus)
    Arrival time: June 5 at
    Destination city: Tampa
    Destination location: Tampa Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Yesterday at 9:28 PM PDT.

Prices and availability are subject to change.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from San Diego to Tampa

Average PriceUS$351 - US$508Average Duration2d 20h
84kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Average PriceUS$488 - US$664Average Duration3d 19h
306kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from San Diego to Tampa

Among the sustainable travel choices, the bus stands out as a good way to reach Tampa. The journey takes about 2 days, 20 hours 15 minutes, and with fares starting at just US$351, it presents an excellent value for a comfortable ride.

20bus per day
2d 20hAverage Duration
US$351Cheapest ticket
84kgCO₂ emissions

Bus San Diego to Tampa: Trip Overview

Average Ticket PriceUS$447
Average Bus Trip Duration2d 20h
Number of daily buses20
Earliest bus departure7:15am
Distance3363 km
Latest bus departure7:35pm

San Diego to Tampa Bus

With Busbud, comparing and booking tickets for a bus from San Diego to Tampa is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from San Diego to Tampa from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Tampa from San Diego, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip San Diego (CA), US - Tampa

  1. How long is the trip from San Diego to Tampa by bus?

    The trip from San Diego to Tampa will take on average 2d 20h. If you're looking for the fastest way to get there, you'll find a bus doing the trip in about 2d 17h.

  2. What is the travel distance from San Diego to Tampa?

    It's about 3361 km (2084 miles) from San Diego to Tampa.

  3. What are the departure and arrival locations for buses traveling from San Diego to Tampa?

    Buses departing from Mission Valley Sheraton in San Diego will take you to Tampa 13th Avenue Bus Stop (McDonald's) in Tampa.

  4. What is the cheapest way to travel from San Diego to Tampa?

    If you're on a budget, consider traveling by bus to Tampa from San Diego; it tends to be more affordable. With a starting ticket price of US$351, this bus becomes your top pick for this journey.

  5. How much does the bus ticket cost from San Diego to Tampa?

    You can expect to pay around US$447 for the bus ride from San Diego to Tampa.

  6. Is there an overnight bus from San Diego to Tampa?

    Yes! If you're heading from San Diego to Tampa, you'll find buses departing until 7:35pm and arriving the next day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05-30
No data
05-31
No data
Today
No data
06-02
US$621
06-03
No data
06-04
No data
06-05
No data
06-06
No data
busbud logoThe cheapest trip from San Diego to Tampa was searched and found on Jun 2, 2025 with a price of US$621

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego to Tampa, as early as possible.

You can expect to pay from US$621 to US$621 for a bus ticket from San Diego to Tampa based on the last 2 days. You can expect to find the cheapest price for the trip at US$621 which is on 2025-06-02.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from San Diego to Tampa.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from San Diego to Tampa, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from San Diego to Tampa.

Tune out to the fine sounds of your best music playlist on your bus trip from San Diego to Tampa while indulging in miles on end of beautiful scenic views.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

What's the cheapest way to go from San Diego to Tampa?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to San Diego by bus?

Bus from San Diego to Tampa

You can also go to Tampa by train

Train from San Diego to Tampa

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

Popular Buses Connecting San Diego

Buses Leaving from San Diego

Buses Going to San Diego

Popular Buses Connecting Tampa

Buses Leaving from Tampa

Buses Going to Tampa