Bus Tickets from Roanoke to Indianapolis

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TomorrowJun 25
from US$98
ThuJun 26
FriJun 27
SatJun 28
SunJun 29
MonJun 30
from US$141
TueJul 1
WedJul 2

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: June 25 at
    Departure city: Roanoke
    Departure location: Roanoke Bus Stop
    Arrival time: June 26 at
    Destination city: Indianapolis
    Destination location: Downtown Transit Center
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: June 25 at
    Departure city: Roanoke
    Departure location: Roanoke Bus Stop
    Arrival time: June 26 at
    Destination city: Indianapolis
    Destination location: Indianapolis Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 25 at
    Departure city: Roanoke
    Departure location: Roanoke Bus Stop
    Arrival time: June 26 at
    Destination city: Indianapolis
    Destination location: Indianapolis Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 25 at
    Departure city: Roanoke
    Departure location: Roanoke Bus Stop
    Arrival time: June 26 at
    Destination city: Indianapolis
    Destination location: Downtown Transit Center
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:

Last refresh of the prices: Last Wednesday at 11:53 PM EDT.

Prices and availability are subject to change.

Accepted payments

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  • China Union Pay
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Compare 2 ways to go from Roanoke to Indianapolis

Bus
Average PriceUS$82 - US$201Average Duration19h 35m
15kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$94 - US$222Average Duration20h 37m
55kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Roanoke to Indianapolis

Among the sustainable travel choices, the bus stands out as a good way to reach Indianapolis. The journey takes about 19 hours 35 minutes, and with fares starting at just US$82, it presents an excellent value for a comfortable ride.

3bus per day
19h 35mAverage Duration
US$82Cheapest ticket
15kgCO₂ emissions

Bus Roanoke to Indianapolis: Trip Overview

Average Ticket PriceUS$136
Average Bus Trip Duration19h 35m
Number of daily buses3
Earliest bus departure4:25am
Distance607 km
Latest bus departure12:50pm

Roanoke to Indianapolis Bus

With Busbud, comparing and booking tickets for a bus from Roanoke to Indianapolis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Roanoke to Indianapolis will be provided by the most trusted bus companies.

Discover how much the bus trip from Roanoke to Indianapolis will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Roanoke - Indianapolis

  1. What is the travel distance from Roanoke to Indianapolis?

    The distance between Roanoke and Indianapolis is around 609 km (378 miles).

  2. What are the departure and arrival locations for buses traveling from Roanoke to Indianapolis?

    Buses traveling this route start their trip at Salem - Exit 140 Park & Ride, in Roanoke, and end it at Greyhound Amtrak Station, in Indianapolis.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06-22
US$161
06-23
No data
Today
US$106
06-25
US$117
06-26
No data
06-27
No data
06-28
No data
06-29
No data
busbud logoThe cheapest trip from Roanoke to Indianapolis was searched and found on Jun 24, 2025 with a price of US$106

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Roanoke to Indianapolis, as early as possible.

You can expect to pay from US$106 to US$161 for a bus ticket from Roanoke to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at US$117 which is on 2025-06-25.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Roanoke to Indianapolis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Roanoke to Indianapolis, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Roanoke to Indianapolis will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Roanoke to Indianapolis, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Roanoke by bus?

Bus from Roanoke to Indianapolis

You can also go to Indianapolis by train

Train from Roanoke to Indianapolis

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