Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Pittsburgh Intermodal Station | 409 Townsend St, SF | Cheapest | ||||
 | Bus | Pittsburgh Intermodal Station | San Francisco Bus Station | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Pittsburgh Intermodal Station | 409 Townsend St, SF | No tags |
Last refresh of the prices: Last Monday at 10:56 AM EST.
Get from Pittsburgh to San Francisco
The journey takes about 2 days, 23 hours 25 minutes, and with fares starting at just $281, it presents an excellent value for a comfortable ride.
Where are the popular stops in Pittsburgh and San Francisco?
Stops in Pittsburgh
- A55 11th St, Pittsburgh, PA 15222, USA
- B
Sennott Square
201 S Bouquet St, Pittsburgh, PA 15213, USA
Stops in San Francisco
- A
Hyde/Beach (Fisherman's Wharf)
700 Beach Street, San Francisco, CA 94109, USA - B
Powell Station
25 Cyril Magnin St , San Francisco, CA 94102-2812 - C
Union Square Hilton
255 Mason St,, San Francisco, CA 94102-2114 - D
San Francisco Greyhound Station
200 Folsom St, San Francisco, CA 94105 - E
444 Townsend St.
444 Townsend St, San Francisco, CA 94107, USA
Compare bus companies
Based on 87501 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $283
Frequently asked questions about travelling from Pittsburgh to San Francisco, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Pittsburgh to San Francisco?
The cheapest bus tickets from Pittsburgh to San Francisco start from $281. The average price for this route is around $699. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Pittsburgh to San Francisco?
The average bus travel time from Pittsburgh to San Francisco is 2d 23h, covering a distance of 3635 km. The quickest bus can get you there in 2d 14h and is operated by Greyhound.
Which bus companies service the Pittsburgh to San Francisco route?
Several major bus companies operate on this route with 3 buses available per day.
What are the earliest and latest departure times for the bus from Pittsburgh to San Francisco?
The earliest bus departs from Pittsburgh to San Francisco at 1:35am. And the latest bus departs at 8:00pm.
What are the CO₂ emissions for the bus trip from Pittsburgh to San Francisco?
A bus trip from Pittsburgh to San Francisco generates an estimated 91 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Pittsburgh to San Francisco, US was searched and found on Jan 19, 2026 with a price of $273To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pittsburgh to San Francisco, US, as early as possible.
You can expect to pay from $273 to $707 for a bus ticket from Pittsburgh to San Francisco, US based on the last 2 days. You can expect to find the cheapest price for the trip at $273 which is on 2026-01-19.
