Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Terminal de Autobuses de Panguipulli | Terminal Sur | Cheapest | ||||
 | Bus | Terminal de Autobuses de Panguipulli | Terminal Sur | Fastest | ||||
 | Bus | Terminal de Autobuses de Panguipulli | Terminal Sur | No tags | ||||
| Bus | Terminal de Autobuses de Panguipulli | Terminal Sur | No tags | ||||
| Bus | Terminal de Autobuses de Panguipulli | Terminal Sur | No tags |
Last refresh of the prices: Last Friday at 3:20 PM -03.
Get from Panguipulli to Santiago
The journey takes about 10 hours, and with fares starting at just $17, it presents an excellent value for a comfortable ride.
Where are the popular stops in Panguipulli and Santiago?
Stops in Panguipulli
- A
Terminal de Autobuses de Panguipulli
Diego Portales 269, Panguipulli, Región de los Ríos, Chile - B
Terminal Tur Bus de Panguipulli
José Miguel Carrera 784, Panguipulli, Región de los Ríos, Chile
Stops in Santiago
- ASantiago - Av Libertador Bernardo O'Higgins 3850, Santiago, Estación Central, Región Metropolitana, Chile
- B
San Borja
San Francisco de Borja 199-225, Santiago, Estación Central, Región Metropolitana, Chile - CTucapel Jiménez 21, 8340528 Santiago, Región Metropolitana, Chile
- DPdte. Riesco 6391-6399, Las Condes, Región Metropolitana, Chile
- EAv. Gral. Oscar Bonilla 418, Lo Prado, Región Metropolitana, Chile
- F
Santiago
Juan Esteban Montero 5688, Las Condes, Las Condes, Región Metropolitana, Chile
Compare bus companies
Frequently asked questions about travelling from Panguipulli to Santiago, CL by bus
How far is Panguipulli from Santiago?
It's about 710 km (441 miles) from Panguipulli to Santiago.
What are the departure and arrival locations for buses traveling from Panguipulli to Santiago?
Buses traveling this route start their trip at Terminal de Autobuses de Panguipulli, in Panguipulli, and end it at Terminal Sur, in Santiago.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Panguipulli to Santiago, CL was searched and found on Nov 22, 2025 with a price of $20To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Panguipulli to Santiago, CL, as early as possible.
You can expect to pay from $20 to $43 for a bus ticket from Panguipulli to Santiago, CL based on the last 2 days. You can expect to find the cheapest price for the trip at $21 which is on 2025-11-24.
