Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Panama City Beach Station | Lankershim/Magnolia - North Hollywood | Cheapest | ||||
 | Bus | Panama City Beach Station | Los Angeles Union Station | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Panama City Beach Station | Los Angeles Union Station | No tags | ||||
| Bus | Panama City Beach Station | Los Angeles Union Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Panama City Beach Station | Downtown LA (Flixbus Lot) | No tags |
Last refresh of the prices: Last Tuesday at 8:24 AM CST.
Get from Panama City to Los Angeles
The journey takes about 2 days, 8 hours 55 minutes, and with fares starting at just $274, it presents an excellent value for a comfortable ride.
Where are the popular stops in Panama City and Los Angeles?
Stops in Los Angeles
- A571-581 Gayley Ave, Los Angeles, CA 90024, USA
- B
Ramirez Street bus stop
530 Ramirez St, Los Angeles, CA 90012, USA - C613 Maple Ave, Los Angeles, CA 90014, USA
- E
Downtown Westin Bonaventure
404 S Figueroa St, Los Angeles, CA 90071, USA - F
LAX Airport Holiday Inn
9901 S La Cienega Blvd, Los Angeles, CA 90045, USA
Compare bus companies
Based on 87501 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $276
Frequently asked questions about travelling from Panama City, US to Los Angeles, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Panama City to Los Angeles?
The cheapest bus tickets from Panama City to Los Angeles start from $274. The average price for this route is around $461. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Panama City to Los Angeles?
The average bus travel time from Panama City to Los Angeles is 2d 8h, covering a distance of 3075 km. The quickest bus can get you there in 2d 2h and is operated by Greyhound.
Which bus companies service the Panama City to Los Angeles route?
Several major bus companies operate on this route with 9 buses available per day.
What are the earliest and latest departure times for the bus from Panama City to Los Angeles?
The earliest bus departs from Panama City to Los Angeles at 7:30am. And the latest bus departs at 9:40pm.
What are the CO₂ emissions for the bus trip from Panama City to Los Angeles?
A bus trip from Panama City to Los Angeles generates an estimated 77 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Panama City, US to Los Angeles, US was searched and found on Jan 19, 2026 with a price of $265To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Panama City, US to Los Angeles, US, as early as possible.
You can expect to pay from $265 to $500 for a bus ticket from Panama City, US to Los Angeles, US based on the last 2 days. You can expect to find the cheapest price for the trip at $265 which is on 2026-01-19.
