Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Orlando Bus Station | Knoxville Bus Station | No tags | ||||
Greyhound + FlixBus | Bus | The Florida Mall | Knoxville Bus Station | No tags | ||||
FlixBus + Greyhound | Bus | Orlando Bus Station | Knoxville Bus Station | No tags | ||||
FlixBus + Greyhound | Bus | Orlando Bus Station | Knoxville Bus Station | No tags | ||||
| Bus | Orlando Bus Station | Knoxville Bus Station | No tags |
Get from Orlando to Knoxville
The journey takes about 23 hours 45 minutes, and with fares starting at just $126, it presents an excellent value for a comfortable ride.
Where are the popular stops in Orlando and Knoxville?
Stops in Orlando
- A555 N John Young Pkwy, Orlando, FL 32805
- BRedCoach Station, 1777 McCoy Road, Orlando, FL 32809
- CJet Set Express Terminal, 3718 LB Mcleod Rd., 32805 Orlando, FL,, United States
- D
Disney World
Disney's All-Star Sports Resort, 1701 West Buena Vista Dr., Orlando, FL 32830 - E
International Dr SuperTours Terminal
5419 International Dr, Orlando, FL 32819, USA - F
Seaworld Hotels
10100 International Drive , Orlando, 32821
Stops in Knoxville
- AKnoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA
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Frequently asked questions about travelling from Orlando to Knoxville, TN by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Orlando to Knoxville?
The cheapest bus tickets from Orlando to Knoxville start from $126. The average price for this route is around $212. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Orlando to Knoxville?
The average bus travel time from Orlando to Knoxville is 23h 45m, covering a distance of 861 km. The quickest bus can get you there in 16h 35m and is operated by Greyhound.
Which bus companies service the Orlando to Knoxville route?
What are the earliest and latest departure times for the bus from Orlando to Knoxville?
The earliest bus departs from Orlando to Knoxville at 5:15am. And the latest bus departs at 10:55pm.
What are the CO₂ emissions for the bus trip from Orlando to Knoxville?
A bus trip from Orlando to Knoxville generates an estimated 22 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Orlando to Knoxville?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87463 reviews.
Which bus company has the best Wi-Fi from Orlando to Knoxville?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Orlando to Knoxville?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Orlando to Knoxville?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Orlando to Knoxville, TN was searched and found on Jan 12, 2026 with a price of $147To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to Knoxville, TN, as early as possible.
You can expect to pay from $147 to $275 for a bus ticket from Orlando to Knoxville, TN based on the last 2 days. You can expect to find the cheapest price for the trip at $147 which is on 2026-01-12.
