Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Greyhound Station | Gateway Station | Cheapest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Greyhound Station | Gateway Station | Fastest | ||||
| Bus | Greyhound Station | Saint Louis (Lambert Field) | No tags |
Last refresh of the prices: Today at 12:07 AM CST.
Get from Mobile to St. Louis
The journey takes about 20 hours 20 minutes, and with fares starting at just $184, it presents an excellent value for a comfortable ride.
Where are the popular stops in Mobile and St. Louis?
Compare bus companies
Based on 87500 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $184
Frequently asked questions about travelling from Mobile to St. Louis by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Mobile to St. Louis?
The cheapest bus tickets from Mobile to St. Louis start from $184. The average price for this route is around $210. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Mobile to St. Louis?
The average bus travel time from Mobile to St. Louis is 20h 20m, covering a distance of 906 km. The quickest bus can get you there in 20h 20m and is operated by Greyhound.
Which bus companies service the Mobile to St. Louis route?
Several major bus companies operate on this route with 2 buses available per day.
What are the earliest and latest departure times for the bus from Mobile to St. Louis?
The earliest bus departs from Mobile to St. Louis at 2:40am. And the latest bus departs at 3:55pm.
What are the CO₂ emissions for the bus trip from Mobile to St. Louis?
A bus trip from Mobile to St. Louis generates an estimated 23 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mobile to St. Louis was searched and found on Jan 16, 2026 with a price of $198To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mobile to St. Louis, as early as possible.
You can expect to pay from $198 to $223 for a bus ticket from Mobile to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $198 which is on 2026-01-16.
