Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Greyhound Station | San Diego (Old Town-FlixBus) | Cheapest | ||||
 | Bus | Greyhound Station | Greyhound Bus Stop | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Greyhound Station | San Diego (Old Town-FlixBus) | No tags | ||||
| Bus | Greyhound Station | Greyhound Bus Stop | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Greyhound Station | UCSD Health La Jolla Station | No tags |
Last refresh of the prices: Last Friday at 7:45 PM CST.
Get from Mobile to San Diego
The journey takes about 2 days, 2 hours 20 minutes, and with fares starting at just $327, it presents an excellent value for a comfortable ride.
Where are the popular stops in Mobile and San Diego?
Stops in San Diego
- A
Mission Valley Sheraton
1433 Camino del Rio S, San Diego, CA 92108, USA - B
Old Town Courtyard Marriot
2435 Jefferson St, San Diego, CA 92110, USA - C
Downtown Holiday Inn
1617 1st Ave, San Diego, CA 92101, USA - D
Greyhound Station
1313 National Ave, San Diego, CA 92101, USA - E
Market St. & Park Blvd
601 Park Boulevard, San Diego, CA 92101, USA - F
San Ysidro McDonald's
727 E San Ysidro Blvd, San Diego, CA 92173, USA
Compare bus companies
Based on 87456 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $340
Frequently asked questions about travelling from Mobile to San Diego, CA, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Mobile to San Diego?
The cheapest bus tickets from Mobile to San Diego start from $327. The average price for this route is around $468. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Mobile to San Diego?
The average bus travel time from Mobile to San Diego is 2d 2h, covering a distance of 2754 km. The quickest bus can get you there in 1d 21h and is operated by Greyhound.
Which bus companies service the Mobile to San Diego route?
Several major bus companies operate on this route with 8 buses available per day.
What are the earliest and latest departure times for the bus from Mobile to San Diego?
The earliest bus departs from Mobile to San Diego at 5:55am. And the latest bus departs at 10:30pm.
What are the CO₂ emissions for the bus trip from Mobile to San Diego?
A bus trip from Mobile to San Diego generates an estimated 69 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mobile to San Diego, CA, US was searched and found on Dec 28, 2025 with a price of $386To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mobile to San Diego, CA, US, as early as possible.
You can expect to pay from $386 to $557 for a bus ticket from Mobile to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $423 which is on 2025-12-29.
