Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Minneapolis (U of MN - Huron Blvd) | Sioux Falls | Cheapest | ||||
| Bus | Minneapolis | Sioux Falls | Fastest | ||||
| Bus | Minneapolis (U of MN - Huron Blvd) | Sioux Falls | No tags | ||||
| Bus | Minneapolis | Sioux Falls | No tags | ||||
| Bus | MSP Airport T1 (Minneapolis International Airport) | Sioux Falls | No tags |
Last refresh of the prices: Last Saturday at 8:26 PM CST.
Get from Minneapolis to Sioux Falls
The journey takes about 7 hours 55 minutes, and with fares starting at just $102, it presents an excellent value for a comfortable ride.
Where are the popular stops in Minneapolis and Sioux Falls?
Stops in Minneapolis
- A
Greyhound Station
950 Hawthorne Ave, Minneapolis, MN 55403, USA - B
MSP Airport
Ground Transportation Center, Terminal 1, 6498 34th Ave S, St Paul, MN 55111, USA
Stops in Sioux Falls
- A
Jefferson Lines Station I-29 & Maple St
4101 W Maple St, Sioux Falls, SD 57107, USA
Compare bus companies
Based on 759 reviews, the company was rated 3.9 stars on Busbud. Travellers were especially satisfied with the temperature and the seats but often complained with the WiFi. Jefferson Lines ticket prices on this trip start at $102
Jefferson Lines Minneapolis Sioux Falls recent customer reviews
I was at the appropriate bus pick up location and no bus showed up. I had to take the metro to the Jefferson/Greyhound station to get on a bus. There was also little to no information about Jefferson at the MSP airport. Overall, very dissatisfied and upset.
Samuel S.
Got the impression that this was the first time this driver had done this route - she got lost twice. Not her fault, Jefferson should be training staff properly and getting new drivers to shadow routes before driving them, or have an experienced driver with them the first few times they do a new route.
Tim G.
I missed my bus and can’t change the bus ticket. I’m stuck at the airport.
Randy K.
Frequently asked questions about travelling from Minneapolis to Sioux Falls by bus
What is the travel distance from Minneapolis to Sioux Falls?
It's about 321 km (199 miles) from Minneapolis to Sioux Falls.
What are the departure and arrival locations for buses traveling from Minneapolis to Sioux Falls?
Buses traveling this route start their trip at Greyhound Station, in Minneapolis, and end it at Jefferson Lines Station I-29 & Maple St, in Sioux Falls.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Minneapolis to Sioux Falls was searched and found on Nov 25, 2025 with a price of $99To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Minneapolis to Sioux Falls, as early as possible.
You can expect to pay from $99 to $268 for a bus ticket from Minneapolis to Sioux Falls based on the last 2 days. You can expect to find the cheapest price for the trip at $99 which is on 2025-11-25.
