Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Melipeuco | Terminal Sur | Cheapest | ||||
| Bus | Melipeuco | Terminal Sur | Fastest | ||||
| Bus | Melipeuco | Terminal Sur | No tags | ||||
 | Bus | Melipeuco | Terminal Sur | No tags |
Last refresh of the prices: Last Tuesday at 10:03 AM -03.
Get from Melipeuco to Santiago
The journey takes about 10 hours 10 minutes, and with fares starting at just $22, it presents an excellent value for a comfortable ride.
Where are the popular stops in Melipeuco and Santiago?
Stops in Melipeuco
- A
Terminal Melipeuco
Pincheira, Melipeuco, IX Región, Chile
Stops in Santiago
- ASantiago - Av Libertador Bernardo O'Higgins 3850, Santiago, Estación Central, Región Metropolitana, Chile
- B
San Borja
San Francisco de Borja 199-225, Santiago, Estación Central, Región Metropolitana, Chile - CTucapel Jiménez 21, 8340528 Santiago, Región Metropolitana, Chile
- DPdte. Riesco 6391-6399, Las Condes, Región Metropolitana, Chile
- EAv. Gral. Oscar Bonilla 418, Lo Prado, Región Metropolitana, Chile
- F
Santiago
Juan Esteban Montero 5688, Las Condes, Las Condes, Región Metropolitana, Chile
Compare bus companies
Frequently asked questions about travelling from Melipeuco to Santiago, CL by bus
What is the distance between Melipeuco and Santiago?
The distance covered from Melipeuco to Santiago is 613 km (380 miles).
What are the departure and arrival locations for buses traveling from Melipeuco to Santiago?
Buses traveling this route start their trip at Terminal Melipeuco, in Melipeuco, and end it at Terminal Sur, in Santiago.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Melipeuco to Santiago, CL was searched and found on Nov 27, 2025 with a price of $20To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Melipeuco to Santiago, CL, as early as possible.
You can expect to pay from $20 to $34 for a bus ticket from Melipeuco to Santiago, CL based on the last 2 days. You can expect to find the cheapest price for the trip at $32 which is on 2025-11-28.
