Bus from Lyon to Brussels: Tickets & Schedules

Next bus departures

Next departures for Lyon to Brussels on November 28
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixbusBus
Perrache
Brussels South (Gare du Midi)CheapestFastest
BlaBlaCar BusBus
    		Lyon - Perrache Bus Station
    		Brussels-South (Gare du Midi)No tags
    FlixbusBus
    		Aéroport LYS
    		Brussels North Train StationNo tags
    BlaBlaCar BusBus
      		Lyon - Perrache Bus Station
      		Brussels-South (Gare du Midi)No tags
      FlixbusBus
      		Aéroport LYS
      		Brussels North Train StationNo tags

      Last refresh of the prices: Today at 11:17 PM CET.

      Compare 3 ways to go from Lyon to Brussels

      We recommend taking the train

      Among the sustainable travel choices, the train stands out as a good way to reach Brussels. The journey takes about 4 hours 13 minutes, and with fares starting at just $100, it presents an excellent value for a comfortable ride.

      19train per day
      4h 13mAverage Duration
      566 kmDistance
      14kgCO₂ emissions
      Bus
      		Average Price$38 - $266Average Duration11h 55m
      14kg CO₂e
      Train
      		Average Price$100 - $381Average Duration4h 13m
      14kg CO₂e
      Carpool
      		Average Price$64 - $157Average Duration7h 30m
      24kg CO₂e

      Frequently asked questions about travelling from Lyon to Brussels by bus

      Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

      1. How much is the bus ticket from Lyon to Brussels?

        The cheapest bus tickets from Lyon to Brussels start from $38. The average price for this route is around $82. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

      2. How long is the bus ride from Lyon to Brussels?

        The average bus travel time from Lyon to Brussels is 11h 55m, covering a distance of 567 km. The quickest bus can get you there in 8h 40m and is operated by BlaBlaCar Bus.

      3. Which bus companies service the Lyon to Brussels route?

        Several major bus companies operate on this route with 15 buses available per day, including services from FlixBus, BlaBlaCar Bus.

      4. What are the earliest and latest departure times for the bus from Lyon to Brussels?

        The earliest bus departs from Lyon to Brussels at 12:20am. And the latest bus departs at 11:59pm.

      5. What are the CO₂ emissions for the bus trip from Lyon to Brussels?

        A bus trip from Lyon to Brussels generates an estimated 14 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

      6. What is the best bus company from Lyon to Brussels?

        According to Busbud customers, the highest-rated bus company on this route is BlaBlaCar Bus, with an average rating of 3.7 out of 5 stars based on 11143 reviews.

      7. Which bus company has the best Wi-Fi from Lyon to Brussels?

        Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.

      8. Which bus company has the best on-time performance from Lyon to Brussels?

        According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

      9. Which bus company has the cleanest buses from Lyon to Brussels?

        According to Busbud traveller reviews, the bus company with the cleanest buses on this route is BlaBlaCar Bus, with a cleanliness rating of 4.3 out of 5 stars.

      Find cheapest prices for buses

      Price is for a one-way ticket for one passenger and based on past searches.

      Best price found
      11-25
      $86
      11-26
      $78
      Today
      $81
      11-28
      $84
      11-29
      $52
      11-30
      $69
      12-01
      $41
      12-02
      $47
      busbud logoThe cheapest trip from Lyon to Brussels was searched and found on Dec 1, 2025 with a price of $41

      To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lyon to Brussels, as early as possible.

      You can expect to pay from $41 to $205 for a bus ticket from Lyon to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at $41 which is on 2025-12-01.

      Usually BlaBlaCar Bus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

      What's the cheapest way to go from Lyon to Brussels?

      busbud logoThe bus is the cheapest travel choice for this destination

      People from around the world trust Busbud

      ‌