Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Los Angeles Union Station | 1116 Woodruff Rd | Cheapest | ||||
 | Bus | Los Angeles Union Station | 1116 Woodruff Rd | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Downtown LA (Flixbus Lot) | 1116 Woodruff Rd | No tags | ||||
| Bus | Lankershim/Magnolia - North Hollywood | 1116 Woodruff Rd | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Lankershim/Magnolia - North Hollywood | 1116 Woodruff Rd | No tags |
Last refresh of the prices: Last Tuesday at 9:40 AM PST.
Compare 2 ways to go from Los Angeles to Greenville
Among the sustainable travel choices, the Bus stands out as a good way to reach Greenville. The journey takes about 2 days, 9 hours 20 minutes, and with fares starting at just $252, it presents an excellent value for a comfortable ride.
Where are the popular stops in Los Angeles and Greenville?
Stops in Los Angeles
- A571-581 Gayley Ave, Los Angeles, CA 90024, USA
- B
Ramirez Street bus stop
530 Ramirez St, Los Angeles, CA 90012, USA - C613 Maple Ave, Los Angeles, CA 90014, USA
- E
Downtown Westin Bonaventure
404 S Figueroa St, Los Angeles, CA 90071, USA - F
LAX Airport Holiday Inn
9901 S La Cienega Blvd, Los Angeles, CA 90045, USA
Compare bus companies
Frequently asked questions about travelling from Los Angeles, US to Greenville, SC by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Los Angeles to Greenville?
The cheapest bus tickets from Los Angeles to Greenville start from $252. The average price for this route is around $398. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Los Angeles to Greenville?
The average bus travel time from Los Angeles to Greenville is 2d 9h, covering a distance of 3278 km. The quickest bus can get you there in 2d 4h and is operated by Greyhound.
Which bus companies service the Los Angeles to Greenville route?
What are the earliest and latest departure times for the bus from Los Angeles to Greenville?
The earliest bus departs from Los Angeles to Greenville at 7:10am. And the latest bus departs at 11:30pm.
What are the CO₂ emissions for the bus trip from Los Angeles to Greenville?
A bus trip from Los Angeles to Greenville generates an estimated 82 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Los Angeles to Greenville?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87500 reviews.
Which bus company has the best Wi-Fi from Los Angeles to Greenville?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Los Angeles to Greenville?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Los Angeles to Greenville?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Los Angeles, US to Greenville, SC was searched and found on Jan 21, 2026 with a price of $242To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Los Angeles, US to Greenville, SC, as early as possible.
You can expect to pay from $242 to $426 for a bus ticket from Los Angeles, US to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at $242 which is on 2026-01-21.
What's the cheapest way to go from Los Angeles, US to Greenville, SC?
The Bus is the cheapest travel choice for this destination
