Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Lake City Bus Station | Houston Bus Station | Cheapest | ||||
 | Bus | Lake City Bus Stop | Houston Lockwood, (TX - TBC Lockwood) | Fastest | ||||
| Bus | Lake City Bus Station | Houston Bus Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Lake City Bus Station | Houston Bus Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Lake City Bus Station | Downtown Gray & Smith | No tags |
Last refresh of the prices: Today at 6:23 AM EST.
Get from Lake City to Houston
The journey takes about 22 hours 5 minutes, and with fares starting at just $232, it presents an excellent value for a comfortable ride.
Where are the popular stops in Lake City and Houston?
Stops in Lake City
- A2470 W US HWY 90, Lake City, FL 32025, USA
- B
Lake City Greyhound Bus Station
251 S MARION AVE , 32055, Florida
Stops in Houston
- A
Hillcroft Ave & Southwest Freeway
6590 Southwest Fwy, Houston, TX 77074, USA - B
Downtown Greyhound Station
2121 Main St, Houston, TX 77002 - C
Harrisburg Greyhound Station
7000 Harrisburg Blvd, Houston, TX 77011, USA - D7011 Harrisburg Blvd, Houston, TX 77011, USA
- E
Clay St & Louisiana St
600-698 Clay St, Houston, TX 77002, USA - F
Lockwood Dr & Harvey Wilson Dr
820 Lockwood Dr, Houston, TX 77002, USA
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Frequently asked questions about travelling from Lake City to Houston, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Lake City to Houston?
The cheapest bus tickets from Lake City to Houston start from $232. The average price for this route is around $306. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Lake City to Houston?
The average bus travel time from Lake City to Houston is 22h 5m, covering a distance of 1221 km. The quickest bus can get you there in 13h 40m and is operated by Tornado Bus.
Which bus companies service the Lake City to Houston route?
Several major bus companies operate on this route with 11 buses available per day, including services from Greyhound, Tornado Bus.
What are the earliest and latest departure times for the bus from Lake City to Houston?
The earliest bus departs from Lake City to Houston at 9:35am. And the latest bus departs at 7:30pm.
What are the CO₂ emissions for the bus trip from Lake City to Houston?
A bus trip from Lake City to Houston generates an estimated 31 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Lake City to Houston?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87500 reviews.
Which bus company has the best Wi-Fi from Lake City to Houston?
Based on Busbud reviews, the bus company Tornado Bus has the highest Wi-Fi rating with a score of 3.9.
Which bus company has the best on-time performance from Lake City to Houston?
According to Busbud traveller reviews, the most punctual bus company on this route is Tornado Bus, with a punctuality rating of 3.4 out of 5 stars.
Which bus company has the cleanest buses from Lake City to Houston?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Tornado Bus, with a cleanliness rating of 4.4 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Lake City to Houston, US was searched and found on Jan 29, 2026 with a price of $190To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lake City to Houston, US, as early as possible.
You can expect to pay from $190 to $245 for a bus ticket from Lake City to Houston, US based on the last 2 days. You can expect to find the cheapest price for the trip at $190 which is on 2026-01-29.
Usually Tornado Bus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
