Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Valley Transit + Greyhound + FlixBus | Bus | Lafayette Transit System | Balboa Park | No tags | ||||
FlixBus + Greyhound | Bus | Lafayette Transit System | UCSD Health La Jolla Station | No tags | ||||
 | Bus | Lafayette Transit System | Greyhound Bus Stop | No tags | ||||
FlixBus + Greyhound | Bus | Lafayette Transit System | Downtown SD (Seaport) | No tags | ||||
Greyhound + FlixBus | Bus | Lafayette Transit System | San Diego (Old Town-FlixBus) | No tags |
Compare 2 ways to go from Lafayette to San Diego
Among the sustainable travel choices, the train stands out as a good way to reach San Diego. The journey takes about 1 day, 23 hours 40 minutes, and with fares starting at just $304, it presents an excellent value for a comfortable ride.
Where are the popular stops in Lafayette and San Diego?
Stops in Lafayette
- A1701 N University Ave, Lafayette, LA 70507, USA
- B
Lafayette A and J Travel Bus Station
100 Lee Ave, Lafayette, LA 70501 - C
Lafayette Bus Stop
2405 Cameron St, Lafayette, LA, USA
Stops in San Diego
- A
Mission Valley Sheraton
1433 Camino del Rio S, San Diego, CA 92108, USA - B
Old Town Courtyard Marriot
2435 Jefferson St, San Diego, CA 92110, USA - C
Downtown Holiday Inn
1617 1st Ave, San Diego, CA 92101, USA - D
Greyhound Station
1313 National Ave, San Diego, CA 92101, USA - E
Market St. & Park Blvd
601 Park Boulevard, San Diego, CA 92101, USA - F
San Ysidro McDonald's
727 E San Ysidro Blvd, San Diego, CA 92173, USA
Compare bus companies
Frequently asked questions about travelling from Lafayette, LA to San Diego, CA, US by bus
How far is Lafayette from San Diego?
The distance covered from Lafayette to San Diego is 2398 km (1487 miles).
What are the departure and arrival locations for buses traveling from Lafayette to San Diego?
Buses traveling this route start their trip at TA Travel Center - Lafayette, in Lafayette, and end it at Mission Valley Sheraton, in San Diego.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Lafayette, LA to San Diego, CA, US was searched and found on Nov 29, 2025 with a price of $382To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lafayette, LA to San Diego, CA, US, as early as possible.
You can expect to pay from $382 to $728 for a bus ticket from Lafayette, LA to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $382 which is on 2025-11-29.
What's the cheapest way to go from Lafayette, LA to San Diego, CA, US?
The bus is the cheapest travel choice for this destination
