Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound | Bus | Jacksonville Bus Station | Buffalo (BUF) Airport | No tags | ||||
Greyhound + FlixBus | Bus | Jacksonville Bus Station | Buffalo (BUF) Airport | No tags | ||||
 | Bus | Jacksonville Bus Station | Niagara Frontier Transportation Authority | No tags | ||||
 | Bus | Jacksonville Bus Station | Niagara Frontier Transportation Authority | No tags | ||||
| Bus | Jacksonville Bus Station | Buffalo (BUF) Airport | No tags |
Compare 2 ways to go from Jacksonville to Buffalo
Among the sustainable travel choices, the train stands out as a good way to reach Buffalo. The journey takes about 1 day, 4 hours 31 minutes, and with fares starting at just $304, it presents an excellent value for a comfortable ride.
Where are the popular stops in Jacksonville and Buffalo?
Stops in Jacksonville
- A
W Forsyth St
1111 W Forsyth St, Jacksonville, FL 32204, USA - B3570 Clifford Ln, Jacksonville, FL 32209, USA
- C
Kings Avenue Station
1003 Kings Avenue, Jacksonville, FL 32207 - D
JRTC Greyhound Bus Station
111 W. Forsyth St, Jacksonville, FL 32202, USA
Stops in Buffalo
- B185 Ellicott St, Buffalo, NY 14203, USA
- C75 Exchange St, Buffalo, NY 14203, USA
Compare bus companies
Frequently asked questions about travelling from Jacksonville, FL to Buffalo, NY by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Jacksonville to Buffalo?
The cheapest bus tickets from Jacksonville to Buffalo start from $224. The average price for this route is around $343. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Jacksonville to Buffalo?
The average bus travel time from Jacksonville to Buffalo is 1d 7h, covering a distance of 1418 km. The quickest bus can get you there in 1d 3h and is operated by FlixBus.
Which bus companies service the Jacksonville to Buffalo route?
What are the earliest and latest departure times for the bus from Jacksonville to Buffalo?
The earliest bus departs from Jacksonville to Buffalo at 8:25am. And the latest bus departs at 6:30pm.
What are the CO₂ emissions for the bus trip from Jacksonville to Buffalo?
A bus trip from Jacksonville to Buffalo generates an estimated 35 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Jacksonville to Buffalo?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11648 reviews.
Which bus company has the best Wi-Fi from Jacksonville to Buffalo?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Jacksonville to Buffalo?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Jacksonville to Buffalo?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Jacksonville, FL to Buffalo, NY was searched and found on Dec 22, 2025 with a price of $489To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jacksonville, FL to Buffalo, NY, as early as possible.
What's the cheapest way to go from Jacksonville, FL to Buffalo, NY?
The bus is the cheapest travel choice for this destination
