Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Tornado Bus + Expreso | Bus | Houston Lockwood, (TX - TBC Lockwood) | Des Moines, (IA - Diversity Insurance/Seguros Mundo Latino) | CheapestFastest | ||||
 | Bus | Houston Lockwood, (TX - TBC Lockwood) | Des Moines, (IA - Diversity Insurance/Seguros Mundo Latino) | No tags |
Last refresh of the prices: Yesterday at 3:22 PM CST.
Get from Houston to Des Moines
The journey takes about 21 hours 51 minutes, and with fares starting at just $325, it presents an excellent value for a comfortable ride.
Where are the popular stops in Houston and Des Moines?
Stops in Houston
- A
Hillcroft Ave & Southwest Freeway
6590 Southwest Fwy, Houston, TX 77074, USA - B2121 Main St, Houston, TX 77002
- C
Harrisburg Greyhound Station
7000 Harrisburg Blvd, Houston, TX 77011, USA - D7011 Harrisburg Blvd, Houston, TX 77011, USA
- E
Clay St & Louisiana St
600-698 Clay St, Houston, TX 77002, USA - F
Lockwood Dr & Harvey Wilson Dr
820 Lockwood Dr, Houston, TX 77002, USA
Stops in Des Moines
- A
Jefferson/Trailways Depot
1501 2nd Ave North, Des Moines, IA 50314 - B
1514 East Grand Ave
1514 East Grand Avenue,, Des Moins, IA, 50316
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Frequently asked questions about travelling from Houston, US to Des Moines by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Houston to Des Moines?
The cheapest bus tickets from Houston to Des Moines start from $325. The average price for this route is around $325. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Houston to Des Moines?
The average bus travel time from Houston to Des Moines is 21h 51m, covering a distance of 1326 km. The quickest bus can get you there in 22h 39m and is operated by Tornado Bus.
Which bus companies service the Houston to Des Moines route?
Several major bus companies operate on this route with 2 buses available per day, including services from Tornado Bus, Greyhound, FlixBus, Valley Transit.
What are the earliest and latest departure times for the bus from Houston to Des Moines?
The earliest bus departs from Houston to Des Moines at 8:30am. And the latest bus departs at 1:30pm.
What are the CO₂ emissions for the bus trip from Houston to Des Moines?
A bus trip from Houston to Des Moines generates an estimated 33 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Houston to Des Moines?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.
Which bus company has the best Wi-Fi from Houston to Des Moines?
Based on Busbud reviews, the bus company Tornado Bus has the highest Wi-Fi rating with a score of 3.6.
Which bus company has the best on-time performance from Houston to Des Moines?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Houston to Des Moines?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Tornado Bus, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Houston, US to Des Moines was searched and found on Nov 29, 2025 with a price of $323To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Houston, US to Des Moines, as early as possible.
You can expect to pay from $323 to $323 for a bus ticket from Houston, US to Des Moines based on the last 2 days. You can expect to find the cheapest price for the trip at $323 which is on 2025-12-01.
