Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Hesperia Main Street | San Ysidro Greyhound Bus Station | CheapestFastest | ||||
 | Bus | 14717 Bear Valley Rd (Carl’s Jr.) | San Ysidro Greyhound Bus Station | No tags | ||||
| Bus | 14717 Bear Valley Rd (Carl’s Jr.) | San Ysidro Greyhound Bus Station | No tags | ||||
| Bus | 14717 Bear Valley Rd (Carl’s Jr.) | San Ysidro Greyhound Bus Station | No tags | ||||
| Bus | 14717 Bear Valley Rd (Carl’s Jr.) | San Ysidro Greyhound Bus Station | No tags |
Last refresh of the prices: Today at 12:55 PM PST.
Get from Hesperia to San Ysidro
The journey takes about 8 hours 25 minutes, and with fares starting at just $123, it presents an excellent value for a comfortable ride.
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Frequently asked questions about travelling from Hesperia to San Ysidro, CA by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Hesperia to San Ysidro?
The cheapest bus tickets from Hesperia to San Ysidro start from $123. The average price for this route is around $141. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Hesperia to San Ysidro?
The average bus travel time from Hesperia to San Ysidro is 8h 25m, covering a distance of 217 km. The quickest bus can get you there in 3h 12m and is operated by Las Vegas Shuttles.
Which bus companies service the Hesperia to San Ysidro route?
Several major bus companies operate on this route with 7 buses available per day, including services from Los Limousines, Las Vegas Shuttles.
What are the earliest and latest departure times for the bus from Hesperia to San Ysidro?
The earliest bus departs from Hesperia to San Ysidro at 1:25am. And the latest bus departs at 4:05pm.
What are the CO₂ emissions for the bus trip from Hesperia to San Ysidro?
A bus trip from Hesperia to San Ysidro generates an estimated 5 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Hesperia to San Ysidro?
According to Busbud customers, the highest-rated bus company on this route is Los Limousines, with an average rating of 3.3 out of 5 stars based on 268 reviews.
Which bus company has the best Wi-Fi from Hesperia to San Ysidro?
Based on Busbud reviews, the bus company Las Vegas Shuttles has the highest Wi-Fi rating with a score of 3.2.
Which bus company has the best on-time performance from Hesperia to San Ysidro?
According to Busbud traveller reviews, the most punctual bus company on this route is Los Limousines, with a punctuality rating of 2.8 out of 5 stars.
Which bus company has the cleanest buses from Hesperia to San Ysidro?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Las Vegas Shuttles, with a cleanliness rating of 4.8 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Hesperia to San Ysidro, CA was searched and found on Dec 3, 2025 with a price of $112To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Hesperia to San Ysidro, CA, as early as possible.
You can expect to pay from $112 to $127 for a bus ticket from Hesperia to San Ysidro, CA based on the last 2 days. You can expect to find the cheapest price for the trip at $112 which is on 2025-12-03.
Usually Los Limousines will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
