Bus from Greenville, SC to Orlando: Tickets & Schedules

Next bus departures

Next departures for Greenville to Orlando on November 28
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
Bus
1116 Woodruff Rd
Orlando Bus StationCheapest
FlixBusBus
1116 Woodruff Rd
Orlando Bus StationFastest
Greyhound Lines, Inc. + FlixBus
Bus
1116 Woodruff Rd
Orlando Bus StationNo tags
FlixBusBus
1116 Woodruff Rd
The Florida MallNo tags
Greyhound Lines, Inc. + FlixBus
Bus
1116 Woodruff Rd
Orlando Bus StationNo tags

Last refresh of the prices: Yesterday at 5:35 PM EST.

Compare 2 ways to go from Greenville to Orlando

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Orlando. The journey takes about 13 hours, and with fares starting at just $99, it presents an excellent value for a comfortable ride.

9bus per day
13hAverage Duration
704 kmDistance
18kgCO₂ emissions
Average Price$99 - $320Average Duration13h
18kg CO₂e
Average Price$250 - $4,119Average Duration1d 8h
65kg CO₂e

Frequently asked questions about travelling from Greenville, SC to Orlando by bus

  1. How far is Greenville from Orlando?

    It's about 710 km (440 miles) from Greenville to Orlando.

  2. What are the departure and arrival locations for buses traveling from Greenville to Orlando?

    Buses departing from Guadalajara Supermarket Bus Stop in Greenville will take you to Orlando Bus Station in Orlando.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11-25
$270
11-26
$290
Today
$216
11-28
$142
11-29
$180
11-30
$224
12-01
$141
12-02
No data
busbud logoThe cheapest trip from Greenville, SC to Orlando was searched and found on Dec 1, 2025 with a price of $141

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Orlando, as early as possible.

You can expect to pay from $141 to $322 for a bus ticket from Greenville, SC to Orlando based on the last 2 days. You can expect to find the cheapest price for the trip at $141 which is on 2025-12-01.

What's the cheapest way to go from Greenville, SC to Orlando?

busbud logoThe bus is the cheapest travel choice for this destination

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