Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | 1116 Woodruff Rd | Downtown Gray & Smith | Cheapest | ||||
 | Bus | Greenville, (SC - Taqueria Guadalajara #3) | Houston Lockwood, (TX - TBC Lockwood) | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | 1116 Woodruff Rd | Houston Bus Station | No tags | ||||
 | Bus | 1116 Woodruff Rd | Houston Bus Station | No tags | ||||
 | Bus | Greenville, (SC - Taqueria Guadalajara #3) | Houston Lockwood, (TX - TBC Lockwood) | No tags |
Last refresh of the prices: Today at 1:49 PM EST.
Compare 2 ways to go from Greenville to Houston
Among the sustainable travel choices, the bus stands out as a good way to reach Houston. The journey takes about 1 day, 30 minutes, and with fares starting at just $159, it presents an excellent value for a comfortable ride.
Where are the popular stops in Greenville and Houston?
Stops in Greenville
- A
Guadalajara Supermarket Bus Stop
2803 White Horse Rd, Greenville, SC 29611 - B
Greenville Bus Station
9 Hendrix DR, Greenville, SC 29607
Stops in Houston
- A
Hillcroft Ave & Southwest Freeway
6590 Southwest Fwy, Houston, TX 77074, USA - B
Downtown Greyhound Station
2121 Main St, Houston, TX 77002 - C
Harrisburg Greyhound Station
7000 Harrisburg Blvd, Houston, TX 77011, USA - D7011 Harrisburg Blvd, Houston, TX 77011, USA
- E
Clay St & Louisiana St
600-698 Clay St, Houston, TX 77002, USA - F
Lockwood Dr & Harvey Wilson Dr
820 Lockwood Dr, Houston, TX 77002, USA
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Frequently asked questions about travelling from Greenville, SC to Houston, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Greenville to Houston?
The cheapest bus tickets from Greenville to Houston start from $159. The average price for this route is around $234. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Greenville to Houston?
The average bus travel time from Greenville to Houston is 1d , covering a distance of 1319 km. The quickest bus can get you there in 15h 14m and is operated by Tornado Bus.
Which bus companies service the Greenville to Houston route?
Several major bus companies operate on this route with 17 buses available per day, including services from Tornado Bus, Greyhound, FlixBus.
What are the earliest and latest departure times for the bus from Greenville to Houston?
The earliest bus departs from Greenville to Houston at 1:20pm. And the latest bus departs at 10:00pm.
What are the CO₂ emissions for the bus trip from Greenville to Houston?
A bus trip from Greenville to Houston generates an estimated 33 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Greenville to Houston?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.
Which bus company has the best Wi-Fi from Greenville to Houston?
Based on Busbud reviews, the bus company Tornado Bus has the highest Wi-Fi rating with a score of 3.6.
Which bus company has the best on-time performance from Greenville to Houston?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Greenville to Houston?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Tornado Bus, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Greenville, SC to Houston, US was searched and found on Dec 5, 2025 with a price of $170To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Houston, US, as early as possible.
You can expect to pay from $170 to $429 for a bus ticket from Greenville, SC to Houston, US based on the last 2 days. You can expect to find the cheapest price for the trip at $170 which is on 2025-12-05.
Usually Tornado Bus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Greenville, SC to Houston, US?
The bus is the cheapest travel choice for this destination
