Bus from Greenville, SC to Gainesville, GA: Tickets & Schedules

Previously seen trips

Next departures for Greenville to Gainesville on December 4
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound + FlixBus
Bus
1116 Woodruff Rd
Gainesville (Mart 24/7)No tags
FlixBus + Greyhound
Bus
1116 Woodruff Rd
Gainesville (Mart 24/7)No tags
GreyhoundBus
1116 Woodruff Rd
Gainesville (Mart 24/7)No tags
Greyhound + FlixBus
Bus
1116 Woodruff Rd
Gainesville (Mart 24/7)No tags
GreyhoundBus
1116 Woodruff Rd
Gainesville (Mart 24/7)No tags

Compare 2 ways to go from Greenville to Gainesville

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach Gainesville. The journey takes about 1 hour 54 minutes, and with fares starting at just $51, it presents an excellent value for a comfortable ride.

1train per day
1h 54mAverage Duration
144 kmDistance
13kgCO₂ emissions
Average Price$50 - $176Average Duration5h 35m
4kg CO₂e
Average Price$51 - $97Average Duration1h 54m
13kg CO₂e

Frequently asked questions about travelling from Greenville, SC to Gainesville, GA by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Greenville to Gainesville?

    The cheapest bus tickets from Greenville to Gainesville start from $50. The average price for this route is around $174. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Greenville to Gainesville?

    The average bus travel time from Greenville to Gainesville is 5h 35m, covering a distance of 142 km. The quickest bus can get you there in 2h 12m and is operated by Tornado Bus.

  3. Which bus companies service the Greenville to Gainesville route?

    Several major bus companies operate on this route with 2 buses available per day, including services from Greyhound, Tornado Bus, FlixBus.

  4. What are the earliest and latest departure times for the bus from Greenville to Gainesville?

    The earliest bus departs from Greenville to Gainesville at 2:45pm. And the latest bus departs at 3:02pm.

  5. What are the CO₂ emissions for the bus trip from Greenville to Gainesville?

    A bus trip from Greenville to Gainesville generates an estimated 4 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

  6. What is the best bus company from Greenville to Gainesville?

    According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.

  7. Which bus company has the best Wi-Fi from Greenville to Gainesville?

    Based on Busbud reviews, the bus company Tornado Bus has the highest Wi-Fi rating with a score of 3.6.

  8. Which bus company has the best on-time performance from Greenville to Gainesville?

    According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Greenville to Gainesville?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Tornado Bus, with a cleanliness rating of 4.5 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
12-02
$165
12-03
$165
Today
$165
12-05
No data
12-06
No data
12-07
No data
12-08
No data
12-09
No data
busbud logoThe cheapest trip from Greenville, SC to Gainesville, GA was searched and found on Dec 2, 2025 with a price of $165

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Gainesville, GA, as early as possible.

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