Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | 1116 Woodruff Rd | Detroit Bus Station | Cheapest | ||||
 | Bus | 1116 Woodruff Rd | Detroit Bus Station | Fastest |
Last refresh of the prices: Yesterday at 2:37 AM EST.
Compare 2 ways to go from Greenville to Detroit
Among the sustainable travel choices, the Bus stands out as a good way to reach Detroit. The journey takes about 19 hours 45 minutes, and with fares starting at just $127, it presents an excellent value for a comfortable ride.
Where are the popular stops in Greenville and Detroit?
Stops in Greenville
Compare bus companies
Frequently asked questions about travelling from Greenville, SC to Detroit, MI by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Greenville to Detroit?
The cheapest bus tickets from Greenville to Detroit start from $127. The average price for this route is around $218. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Greenville to Detroit?
The average bus travel time from Greenville to Detroit is 19h 45m, covering a distance of 837 km. The quickest bus can get you there in 19h 10m and is operated by Greyhound.
Which bus companies service the Greenville to Detroit route?
What are the earliest and latest departure times for the bus from Greenville to Detroit?
The earliest bus departs from Greenville to Detroit at 2:45pm. And the latest bus departs at 10:00pm.
What are the CO₂ emissions for the bus trip from Greenville to Detroit?
A bus trip from Greenville to Detroit generates an estimated 21 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Greenville to Detroit?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87463 reviews.
Which bus company has the best Wi-Fi from Greenville to Detroit?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Greenville to Detroit?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Greenville to Detroit?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Greenville, SC to Detroit, MI was searched and found on Jan 13, 2026 with a price of $150To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Detroit, MI, as early as possible.
You can expect to pay from $150 to $271 for a bus ticket from Greenville, SC to Detroit, MI based on the last 2 days. You can expect to find the cheapest price for the trip at $150 which is on 2026-01-13.
What's the cheapest way to go from Greenville, SC to Detroit, MI?
The Bus is the cheapest travel choice for this destination
