Next departures for Frankfurt am Main to Lyon on November 19
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Frankfurt Hbf
Perrache
CheapestFastest
Bus
FRA Frankfurt airport
Aéroport LYS
No tags
Bus
FRA Frankfurt airport
Perrache
No tags
Bus
FRA Frankfurt airport
Perrache
No tags
Bus
Frankfurt Hbf
Aéroport LYS
No tags
Next departures for Frankfurt am Main to Lyon on November 20
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Frankfurt - Main bus station
Lyon - Perrache Bus Station
Cheapest
Bus
Frankfurt Main Airport P36
Lyon - Perrache Bus Station
Fastest
Bus
Hbf
de Perrache - Galerie A
No tags
Bus
Hbf
Perrache
No tags
Next departures for Frankfurt am Main to Lyon on November 21
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Frankfurt - Main bus station
Lyon - Perrache Bus Station
Cheapest
Bus
Frankfurt Main Airport P36
Lyon - Perrache Bus Station
Fastest
Bus
Frankfurt - Main bus station
Lyon - Perrache Bus Station
No tags
Bus
Frankfurt Main Airport P36
Lyon - Perrache Bus Station
No tags
Next departures for Frankfurt am Main to Lyon on November 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Frankfurt - Main bus station
Lyon - Perrache Bus Station
Cheapest
Bus
Frankfurt Main Airport P36
Lyon - Perrache Bus Station
Fastest
Last refresh of the prices: Today at 11:08 AM CET.
Compare 3 ways to go from Frankfurt am Main to Lyon
We recommend carpooling
Among the sustainable travel choices, the carpool stands out as a good way to reach Lyon. The journey takes about 7 hours 10 minutes, and with fares starting at just $66, it presents an excellent value for a comfortable ride.
Based on 11376 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the WiFi. FlixBus ticket prices on this trip start at $52
Based on 11141 reviews, the company was rated 3.7 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the WiFi. BlaBlaCar Bus ticket prices on this trip start at $55
Based on 1207 reviews, the company was rated 3.6 stars on Busbud. Travellers were especially satisfied with the ticket access and the cleanliness but often complained with the WiFi. Sindbad ticket prices on this trip start at $102
Frequently asked questions about travelling from Frankfurt am Main to Lyon by bus
What is the distance between Frankfurt am Main and Lyon?
The distance between Frankfurt am Main and Lyon is approximately 564 km (350 miles).
What are the departure and arrival locations for buses traveling from Frankfurt am Main to Lyon?
Buses departing from Frankfurt Airport in Frankfurt am Main will take you to Lyon Airport in Lyon.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11-17
$76
11-18
$69
Today
$58
11-20
$52
11-21
$52
11-22
$55
11-23
$52
11-24
$53
The cheapest trip from Frankfurt am Main to Lyon was searched and found on Nov 21, 2025 with a price of $52
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Frankfurt am Main to Lyon, as early as possible.
You can expect to pay from $52 to $106 for a bus ticket from Frankfurt am Main to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at $52 which is on 2025-11-21.
Usually Sindbad will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Frankfurt am Main to Lyon?
The bus is the cheapest travel choice for this destination
The cheapest trip from Frankfurt am Main to Lyon was searched and found on Nov 21, 2025 with a price of $52
The bus is the cheapest travel choice for this destination
