Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound + FlixBus | Bus | Florence, SC | Syracuse (Regional Transportation Center) | No tags | ||||
FlixBus + Greyhound | Bus | Florence, SC | Syracuse (Regional Transportation Center) | No tags | ||||
FlixBus + Greyhound | Bus | Florence, SC | Syracuse (Regional Transportation Center) | No tags | ||||
FlixBus + Greyhound | Bus | Florence, SC | Syracuse (Regional Transportation Center) | No tags | ||||
Greyhound + FlixBus | Bus | Florence, SC | Syracuse (Regional Transportation Center) | No tags |
Compare 2 ways to go from Florence to Syracuse
Among the sustainable travel choices, the bus stands out as a good way to reach Syracuse. The journey takes about 21 hours 15 minutes, and with fares starting at just $197, it presents an excellent value for a comfortable ride.
Where are the popular stops in Florence and Syracuse?
Stops in Florence
- A619 S Irby St, Florence, SC 29501, USA
- B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Stops in Syracuse
- A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208 - CBus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210
- D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA - E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA - F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA
Compare bus companies
Frequently asked questions about travelling from Florence, SC, US to Syracuse, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Florence to Syracuse?
The cheapest bus tickets from Florence to Syracuse start from $197. The average price for this route is around $400. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Florence to Syracuse?
The average bus travel time from Florence to Syracuse is 21h 15m, covering a distance of 1036 km. The quickest bus can get you there in 19h 31m and is operated by FlixBus.
Which bus companies service the Florence to Syracuse route?
What are the earliest and latest departure times for the bus from Florence to Syracuse?
The earliest bus departs from Florence to Syracuse at 12:05am. And the latest bus departs at 4:30pm.
What are the CO₂ emissions for the bus trip from Florence to Syracuse?
A bus trip from Florence to Syracuse generates an estimated 26 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Florence to Syracuse?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87435 reviews.
Which bus company has the best Wi-Fi from Florence to Syracuse?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Florence to Syracuse?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Florence to Syracuse?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Florence, SC, US to Syracuse, US was searched and found on Dec 22, 2025 with a price of $385To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Syracuse, US, as early as possible.
