Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Bus station | New Orleans Bus Station | CheapestFastest | ||||
| Bus | Bus station | New Orleans Bus Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Bus station | New Orleans Bus Station | No tags | ||||
| Bus | Bus station | New Orleans Intl Airport, 900 Airline Dr | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Florence, SC | New Orleans Bus Station | No tags |
Last refresh of the prices: Last Monday at 11:12 AM EST.
Compare 2 ways to go from Florence to New Orleans
Among the sustainable travel choices, the bus stands out as a good way to reach New Orleans. The journey takes about 1 day, 45 minutes, and with fares starting at just $140, it presents an excellent value for a comfortable ride.
Where are the popular stops in Florence and New Orleans?
Stops in Florence
- A619 S Irby St, Florence, SC 29501, USA
- B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
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Frequently asked questions about travelling from Florence, SC, US to New Orleans by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Florence to New Orleans?
The cheapest bus tickets from Florence to New Orleans start from $140. The average price for this route is around $161. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Florence to New Orleans?
The average bus travel time from Florence to New Orleans is 1d , covering a distance of 1080 km. The quickest bus can get you there in 17h 25m and is operated by Greyhound.
Which bus companies service the Florence to New Orleans route?
What are the earliest and latest departure times for the bus from Florence to New Orleans?
The earliest bus departs from Florence to New Orleans at 5:45am. And the latest bus departs at 4:30pm.
What are the CO₂ emissions for the bus trip from Florence to New Orleans?
A bus trip from Florence to New Orleans generates an estimated 27 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Florence to New Orleans?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.
Which bus company has the best Wi-Fi from Florence to New Orleans?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Florence to New Orleans?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Florence to New Orleans?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Florence, SC, US to New Orleans was searched and found on Dec 1, 2025 with a price of $143To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to New Orleans, as early as possible.
You can expect to pay from $143 to $182 for a bus ticket from Florence, SC, US to New Orleans based on the last 2 days. You can expect to find the cheapest price for the trip at $143 which is on 2025-12-01.
What's the cheapest way to go from Florence, SC, US to New Orleans?
The bus is the cheapest travel choice for this destination
