Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Detroit Bus Station | Panama City Beach Station | CheapestFastest | ||||
| Bus | Detroit Bus Station | Panama City Beach Station | No tags |
Last refresh of the prices: Last Monday at 3:20 PM EST.
Get from Detroit to Panama City
The journey takes about 1 day, 3 hours 5 minutes, and with fares starting at just $179, it presents an excellent value for a comfortable ride.
Where are the popular stops in Detroit and Panama City?
Compare bus companies
Based on 87501 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $179
Frequently asked questions about travelling from Detroit, MI to Panama City, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Detroit to Panama City?
The cheapest bus tickets from Detroit to Panama City start from $179. The average price for this route is around $266. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Detroit to Panama City?
The average bus travel time from Detroit to Panama City is 1d 3h, covering a distance of 1372 km. The quickest bus can get you there in 1d 3h and is operated by Greyhound.
Which bus companies service the Detroit to Panama City route?
Several major bus companies operate on this route with 1 buses available per day.
What are the earliest and latest departure times for the bus from Detroit to Panama City?
The earliest bus departs from Detroit to Panama City at 6:40am. And the latest bus departs at 7:30pm.
What are the CO₂ emissions for the bus trip from Detroit to Panama City?
A bus trip from Detroit to Panama City generates an estimated 34 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Detroit, MI to Panama City, US was searched and found on Jan 17, 2026 with a price of $193To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit, MI to Panama City, US, as early as possible.
You can expect to pay from $193 to $230 for a bus ticket from Detroit, MI to Panama City, US based on the last 2 days. You can expect to find the cheapest price for the trip at $193 which is on 2026-01-17.
