Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Detroit Bus Station | Lake City Bus Station | CheapestFastest | ||||
 | Bus | Detroit Bus Station | Lake City Bus Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Detroit Bus Station | Lake City Bus Station | No tags |
Last refresh of the prices: Last Sunday at 8:01 PM EST.
Get from Detroit to Lake City
The journey takes about 1 day, 6 hours 25 minutes, and with fares starting at just $204, it presents an excellent value for a comfortable ride.
Where are the popular stops in Detroit and Lake City?
Stops in Lake City
- A2470 W US HWY 90, Lake City, FL 32025, USA
- B
Lake City Greyhound Bus Station
251 S MARION AVE , 32055, Florida
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Frequently asked questions about travelling from Detroit, MI to Lake City by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Detroit to Lake City?
The cheapest bus tickets from Detroit to Lake City start from $204. The average price for this route is around $284. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Detroit to Lake City?
The average bus travel time from Detroit to Lake City is 1d 6h, covering a distance of 1351 km. The quickest bus can get you there in 1d 6h and is operated by FlixBus.
Which bus companies service the Detroit to Lake City route?
What are the earliest and latest departure times for the bus from Detroit to Lake City?
The earliest bus departs from Detroit to Lake City at 6:40am. And the latest bus departs at 11:25pm.
What are the CO₂ emissions for the bus trip from Detroit to Lake City?
A bus trip from Detroit to Lake City generates an estimated 34 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Detroit to Lake City?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11799 reviews.
Which bus company has the best Wi-Fi from Detroit to Lake City?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Detroit to Lake City?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Detroit to Lake City?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Detroit, MI to Lake City was searched and found on Jan 10, 2026 with a price of $293To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit, MI to Lake City, as early as possible.
You can expect to pay from $293 to $360 for a bus ticket from Detroit, MI to Lake City based on the last 2 days. You can expect to find the cheapest price for the trip at $293 which is on 2026-01-10.
