Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Detroit Bus Station | Lafayette Bus Stop | Cheapest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Detroit Bus Station | Lafayette Bus Stop | Fastest | ||||
 | Bus | Detroit Bus Station | Lafayette Bus Stop | No tags | ||||
 | Bus | Detroit Bus Station | Lafayette Bus Stop | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Detroit Bus Station | Lafayette Bus Stop | No tags |
Last refresh of the prices: Yesterday at 11:36 PM EST.
Compare 2 ways to go from Detroit to Lafayette
Among the sustainable travel choices, the bus stands out as a good way to reach Lafayette. The journey takes about 10 hours, and with fares starting at just $68, it presents an excellent value for a comfortable ride.
Where are the popular stops in Detroit and Lafayette?
Stops in Lafayette
- A
CityBus Center
N 3rd St & North St (Corner), Lafayette, IN 47901
Compare bus companies
Frequently asked questions about travelling from Detroit, MI to Lafayette, IN by bus
What is the travel distance from Detroit to Lafayette?
It's about 380 km (236 miles) from Detroit to Lafayette.
What are the departure and arrival locations for buses traveling from Detroit to Lafayette?
Buses traveling this route start their trip at Detroit Bus Station, in Detroit, and end it at CityBus Center, in Lafayette.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Detroit, MI to Lafayette, IN was searched and found on Nov 27, 2025 with a price of $94To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit, MI to Lafayette, IN, as early as possible.
You can expect to pay from $94 to $142 for a bus ticket from Detroit, MI to Lafayette, IN based on the last 2 days. You can expect to find the cheapest price for the trip at $94 which is on 2025-11-27.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Detroit, MI to Lafayette, IN?
The bus is the cheapest travel choice for this destination
