Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound + FlixBus | Bus | Des Moines | City of Portland | No tags | ||||
FlixBus + Greyhound | Bus | Des Moines | City of Portland | No tags | ||||
FlixBus + Greyhound | Bus | Des Moines | City of Portland | No tags |
Get from Des Moines to Portland
The journey takes about 2 days, 10 hours 5 minutes, and with fares starting at just $320, it presents an excellent value for a comfortable ride.
Where are the popular stops in Des Moines and Portland?
Stops in Des Moines
- A
Jefferson/Trailways Depot
1501 2nd Ave North, Des Moines, IA 50314 - B
1514 East Grand Ave
1514 East Grand Avenue,, Des Moins, IA, 50316
Stops in Portland
- A
Greyhound Station Portland Maine
389 Congress St, Portland, ME 04102, USA
Compare bus companies
Based on 87477 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $320
Frequently asked questions about travelling from Des Moines to Portland, ME by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Des Moines to Portland?
The cheapest bus tickets from Des Moines to Portland start from $320. The average price for this route is around $351. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Des Moines to Portland?
The average bus travel time from Des Moines to Portland is 2d 10h, covering a distance of 1915 km. The quickest bus can get you there in 2d 10h and is operated by Greyhound.
Which bus companies service the Des Moines to Portland route?
Several major bus companies operate on this route with 1 buses available per day.
What are the earliest and latest departure times for the bus from Des Moines to Portland?
The earliest bus departs from Des Moines to Portland at 9:25am. And the latest bus departs at 9:45am.
What are the CO₂ emissions for the bus trip from Des Moines to Portland?
A bus trip from Des Moines to Portland generates an estimated 48 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Des Moines to Portland, ME was searched and found on Jan 1, 2026 with a price of $338To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Des Moines to Portland, ME, as early as possible.
