What is the distance between Denver and Indianapolis?

The distance between Denver and Indianapolis is around 1609 km (998 miles).

What are the departure and arrival locations for buses traveling from Denver to Indianapolis?

Buses traveling this route start their trip at Union Station, in Denver, and end it at Greyhound Amtrak Station, in Indianapolis.

Bus Denver to Indianapolis from $195 | Refundable Tickets

Next bus departures

Next departures for Denver to Indianapolis on November 25
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	7:25pm	DENVER	21h 55m	7:20pm	Indianapolis Bus Station	CheapestFastest
Greyhound Lines, Inc. + FlixBus	Bus	7:00pm	DENVER	1d 2h	11:20pm	Downtown Transit Center	No tags
Greyhound Lines, Inc. + FlixBus	Bus	7:25pm	DENVER	1d 11h	8:25am	Downtown Transit Center	No tags

Next departures for Denver to Indianapolis on November 26
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	7:00pm	DENVER	1d 2h	11:20pm	Downtown Transit Center	Cheapest
	Bus	7:25pm	DENVER	21h 55m	7:20pm	Indianapolis Bus Station	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	7:25pm	DENVER	1d 7h	4:25am	Downtown Transit Center	No tags

Next departures for Denver to Indianapolis on November 27
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	7:25pm	DENVER	21h 55m	7:20pm	Indianapolis Bus Station	CheapestFastest
Greyhound Lines, Inc. + FlixBus	Bus	7:00pm	DENVER	1d 2h	11:20pm	Downtown Transit Center	No tags
Greyhound Lines, Inc. + FlixBus	Bus	7:25pm	DENVER	1d 7h	4:25am	Downtown Transit Center	No tags

Next departures for Denver to Indianapolis on November 28
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	7:25pm	DENVER	21h 55m	7:20pm	Indianapolis Bus Station	CheapestFastest
Greyhound Lines, Inc. + FlixBus	Bus	7:00pm	DENVER	1d 2h	11:20pm	Downtown Transit Center	No tags
Greyhound Lines, Inc. + FlixBus	Bus	7:25pm	DENVER	1d 7h	4:25am	Downtown Transit Center	No tags

Last refresh of the prices: Last Thursday at 11:16 PM MST.

Compare 2 ways to go from Denver to Indianapolis

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach Indianapolis. The journey takes about 1 day, 2 hours 50 minutes, and with fares starting at just $206, it presents an excellent value for a comfortable ride.

1train per day

1d 2hAverage Duration

1608 kmDistance

146kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$174 - $503	Average Duration1d 7h	CO₂ emissions 40kg CO₂e
Train	Average Price$206 - $386	Average Duration1d 2h	CO₂ emissions 146kg CO₂e

Where are the popular stops in Denver and Indianapolis?

Stops in Denver

A
Union Station
1701 Wynkoop St, Denver, CO 80202
Visit page
B
Bus Station
1055 19th St, Denver, CO 80202

Stops in Indianapolis

A
Greyhound Amtrak Station
350 S Illinois St, Indianapolis, IN 46225
Visit page

Compare bus companies

Greyhound

3.5/587,394 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Based on 87394 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $174

Greyhound Denver Indianapolis recent customer reviews

Other than the bus being more than 2 hours late, everything else was good. Cleanliness of stations , restrooms and drivers and staff were excellent. We could have been better informed of delay in Denver. The took our bus off the board and we had no idea what was happening.

Cathy S.

April 2, 2019

Burlington Trailways

4/520 reviews

Staff5

Timeliness5

Cleanliness5

Wifi5

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about travelling from Denver to Indianapolis by bus

What is the distance between Denver and Indianapolis?
The distance between Denver and Indianapolis is around 1609 km (998 miles).
What are the departure and arrival locations for buses traveling from Denver to Indianapolis?
Buses traveling this route start their trip at Union Station, in Denver, and end it at Greyhound Amtrak Station, in Indianapolis.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11-23

$575

11-24

$442

Today

$325

11-26

$300

11-27

$241

11-28

$258

11-29

$362

11-30

$302

The cheapest trip from Denver to Indianapolis was searched and found on Nov 27, 2025 with a price of $241

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Denver to Indianapolis, as early as possible.

You can expect to pay from $241 to $575 for a bus ticket from Denver to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $241 which is on 2025-11-27.